Reward system

Recent articles

Book cover of What Is Intelligence.

‘What Is Intelligence?’: An excerpt

In his new book, published today, Blaise Agüera y Arcas examines the fundamental aspects of intelligence in biological and artificial systems. In this excerpt from Chapter 4, he examines temporal difference, a reinforcement learning algorithm.

By Blaise Agüera y Arcas
23 September 2025 | 9 min read
Research image of mouse brain slices.

Some dopamine neurons signal default behaviors to reinforce habits

Movement-sensing neurons that target the striatum influence a mouse’s choice of action by favoring routine.

By Holly Barker
11 June 2025 | 5 min listen
Research image of neurons in the interpeduncular nucleus.

‘Understudied secret’ in brain dampens nicotine drive in mice

The interpeduncular nucleus produces an aversion to nicotine, even at low doses, and helps moderate how rewarding mice find the drug.

By Lauren Schenkman
4 June 2025 | 5 min listen
Illustration of cranes attempting to assemble a structure out of very small black squares.

In case you missed it: Standout news stories from 2024

These five stories—on the pregnant brain, a failed imaging method and more—top our list of some of the most notable neuroscience research findings this year.

By The Transmitter
23 December 2024 | 2 min read

Vijay Namboodiri and Ali Mohebi on the evolving story of dopamine’s role in cognitive function

Researchers discuss the classic stories of dopamine’s role in learning, ongoing work linking it to a wide variety of cognitive functions, and recent research suggesting that dopamine may help us "look back" to discover the causes of events in the world.

By Paul Middlebrooks
27 September 2024 | 97 min listen
Illustration of cranes attempting to assemble a structure out of very small black squares.

Reconstructing dopamine’s link to reward

The field is grappling with whether to modify the long-standing theory of reward prediction error—or abandon it entirely.

By Angie Voyles Askham
13 September 2024 | 20 min listen
Illustration of cranes attempting to assemble a structure out of very small black squares.

Dopamine and the need for alternative theories

Some experimental findings are inconsistent with the dominant model of reward prediction error, highlighting the need for alternative testable and falsifiable models for dopamine function.

By Vijay Mohan K. Namboodiri
13 September 2024 | 7 min read
Illustration of several structures constructed out of small black squares, with scaffolding on some of the structures.

Does a new theory of dopamine replace the classic model?

My answer would be no, but the model poses challenges that will sharpen our understanding of dopamine and learning.

By Naoshige Uchida
13 September 2024 | 8 min read
A diagram of green neurnons

Cocaine, morphine commandeer neurons normally activated by food, water in mice

Confirming a long-held hypothesis, repeated exposure to the drugs alters neurons in the nucleus accumbens, the brain’s reward center, and curbs an animal’s urge for sustenance.

By Lauren Schenkman
8 May 2024 | 5 min read

Explore more from The Transmitter

Mouse sensory neurons express the ion channel TPRV1 .

Neurons tune electron transport chain to survive onslaught of noxious stimuli

Nociceptors tamp down the production of reactive oxygen species in response to heat, chemical irritants or toxins.

By Viviane Callier
22 October 2025 | 5 min listen

Vicente Raja brings ecological psychology concepts to neuroscience

He suggests neuroscientists should pay more attention to the principles of Gibsonian ecological psychology, such as affordances, ecological information and resonance, to better explain perception and action.

By Paul Middlebrooks
22 October 2025 | 99 min listen
Illustration of a circuit made of sperm-like lines.

Gene variants accumulate in older men’s sperm; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 20 October.

By Jill Adams
21 October 2025 | 2 min read

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