Reward system

Recent articles

A brown mouse between a red cube and blue cylinder looks curiously at the top of the cylinder, standing on hind legs.

Wouldn’t you like to know? A mouse would

Mice seek information for curiosity’s sake—and their desire for knowledge versus a payout is represented distinctly in the brain, new findings suggest.

By Sarah Thau
26 August 2026 | 5 min read
Child sitting on a trampoline.

Study questions DSM-5’s combining of autism traits

Sensory traits and restricted and repetitive behaviors are best understood as distinct but related characteristics, the new work suggests.

By Lauren Schenkman
23 July 2026 | 5 min read
Research image showing dopamine level spikes.

Reward-learning algorithm hardwired into dopamine circuit

The finding bolsters the canonical model of reward prediction error, which has come under scrutiny in recent years.

By Natalia Mesa
5 June 2026 | 5 min read
Howard Fields.

In memoriam: Howard Fields, pain research pioneer

Over six decades, Fields mapped out the circuits of both pain and addiction.

By Natalia Mesa
22 May 2026 | 7 min read
Illustration of a monkey pushing a button.

This paper changed my life: Erin Calipari ponders the nuances of rewarding and aversive stimuli

A 1960s study by Kelleher and Morse found that lever pressing in squirrel monkeys depended not on whether they received a reward or shock, but on the rules of the task. This taught Calipari to think deeply about factors that influence how behavior is generated and maintained.

By Erin Calipari
14 April 2026 | 5 min read
Book cover of What Is Intelligence.

‘What Is Intelligence?’: An excerpt

In his new book, published today, Blaise Agüera y Arcas examines the fundamental aspects of intelligence in biological and artificial systems. In this excerpt from Chapter 4, he examines temporal difference, a reinforcement learning algorithm.

By Blaise Agüera y Arcas
23 September 2025 | 9 min read
Research image of mouse brain slices.

Some dopamine neurons signal default behaviors to reinforce habits

Movement-sensing neurons that target the striatum influence a mouse’s choice of action by favoring routine.

By Holly Barker
11 June 2025 | 4 min read
Research image of neurons in the interpeduncular nucleus.

‘Understudied secret’ in brain dampens nicotine drive in mice

The interpeduncular nucleus produces an aversion to nicotine, even at low doses, and helps moderate how rewarding mice find the drug.

By Lauren Schenkman
4 June 2025 | 4 min read
Illustration of cranes attempting to assemble a structure out of very small black squares.

In case you missed it: Standout news stories from 2024

These five stories—on the pregnant brain, a failed imaging method and more—top our list of some of the most notable neuroscience research findings this year.

By The Transmitter
23 December 2024 | 2 min read

Vijay Namboodiri and Ali Mohebi on the evolving story of dopamine’s role in cognitive function

Researchers discuss the classic stories of dopamine’s role in learning, ongoing work linking it to a wide variety of cognitive functions, and recent research suggesting that dopamine may help us "look back" to discover the causes of events in the world.

By Paul Middlebrooks
27 September 2024 | 97 min listen

Explore more from The Transmitter

Illustrated collage of a monkey profile, a gloved hand holding a vaccine syringe touching an outline of the United States with two primates sitting near it, a strand of DNA, and flags of the United States and China in the background.

U.S. national primate research centers face an uncertain future

The facilities were meant to last 100 years. Four decades shy of that mark, amid flatlined funds and mounting political pressure, their directors are trying to find a path forward.

By Calli McMurray
9 October 2026 | 12 min read
Reflections of primates in lab equipment (bottom left: Rhesus macaque, top left: Pig-tailed macaque, bottom right: Crab-eating macaque. top right: Marmoset

What if nonhuman primate research goes away?

As the U.S. government takes steps to stop using nonhuman primates in research, The Transmitter investigates what that shift could mean for neuroscience.

By The Transmitter
9 October 2026 | 2 min read
Illustration of primate hands interacting with objects of cognitive tests.

The neuroscience questions that need nonhuman primates

The Transmitter asked 17 neuroscientists what questions might remain unanswered if support for nonhuman primate research continues to decline.

By Alissa de Chassey
9 October 2026 | 10 min read