Electrophysiology

Recent articles

Cortical organoids.

Five-year-old human brain organoids aged on schedule

The cultured spheres typically mimic only prenatal development, but the five-year-old ones grown in Paola Arlotta’s lab acquired postnatal features.

By Claudia López Lloreda
19 August 2026 | 5 min read

How BCIs reveal the speaking brain

Long-term implants provide an opportunity to study how speech arises in everyday life.

By Claudia López Lloreda, Rebecca Horne
17 July 2026 | 4 min watch
Research image of cursor movement from high gamma activity.

Recording warning: Common brain signal may be misunderstood

High gamma activity in electrophysiologic recordings reflects widespread neural activity, not merely local firing, as previously thought.

By Claudia López Lloreda
30 June 2026 | 5 min read
Connexiohuman Connexin 26 dodecamer at 90mmHg PCO2, pH7.4

Designer synapses edit brain circuits in living animals

The approach could help elucidate relationships between circuit structure and function, as well as the role of natural electrical synapses.

By Simon Makin
23 June 2026 | 5 min read

Cortical area remixes macaques’ knowledge blocks to solve new problems

When monkeys draw complex shapes, their neural activity reflects patterns of activation elicited by drawing simpler, component shapes.

By Lauren Schenkman
19 June 2026 | 0 min watch

Snoozing dragons stir up ancient evidence of sleep’s dual nature

Deep-sleep cycling between brain waves of higher and lower amplitude dates far back on the evolutionary tree, according to a new comparative study of mammals and reptiles.

By Lauren Schenkman
29 December 2025 | 0 min watch

Facial movements telegraph cognition in mice

If you give a mouse a decision, its thought process may show on its face.

By Lauren Schneider
30 September 2025 | 0 min watch
Illustration of a multiple mouse brains and brain slices converging onto one animal.

Reproducibility is a team sport: Lessons from a large-scale collaboration

Building reproducible systems across labs is possible, even in large-scale neuroscience projects. You just need rigor, collaboration and the willingness to look your own practices dead in the eye.

By Anne Churchland
29 September 2025 | 7 min read
Research image of mouse brain activity during a decision-making task.

Everything everywhere all at once: Decision-making signals engage entire brain

The findings, gleaned from the most comprehensive map yet of brain activity during decision-making in mice, show that the process is even more distributed than previously thought.

By Claudia López Lloreda
3 September 2025 | 5 min read
A James Hudspeth.

Remembering A. James Hudspeth, hair cell explorer

Hudspeth, who died 16 August at age 79, devoted his 50-year career to untangling how the ear converts sound into electrical signals.

By Calli McMurray
21 August 2025 | 7 min read

Explore more from The Transmitter

Speech bubbles progress from light- to dark- colored.

Amid funding uncertainty, neuroscientists report a mix of cynicism, persistence

Two years into one of the most tumultuous tenures in U.S. federal funding, researchers outline how they are coping with ongoing changes and reflect on the impact these changes are having on the system more broadly.

By Emily Singer
28 August 2026 | 5 min read
Stages of neurodegeneration: Neurofibrillary tangles at different stages of neurodegeneration are labeled with phosphorylated tau antibodies (green and blue).

Reimagining Mexico’s brain bank

Since Alzheimer’s disease researcher José Luna-Muñoz assumed leadership of the facility—Latin America’s oldest—in 2011, he has been acquiring additional tissue types and is working to expand donor recruitment to rural areas.

By Alejandra Manjarrez
28 August 2026 | 7 min read

Revealing how crabs make their escape

Houdini-like Neohelice granulata offers a rare opportunity to record intracellularly from awake, behaving animals.

By Natalia Mesa
28 August 2026 | 0 min watch