Neural circuits
Recent articles
Connectomics 2.0: Simulating the brain
With a complete fly connectome in hand, researchers are taking the next step to model how brain circuits fuel function.

Connectomics 2.0: Simulating the brain
With a complete fly connectome in hand, researchers are taking the next step to model how brain circuits fuel function.
‘Perturb and record’ optogenetics probe aims precision spotlight at brain structures
The tool provides a new way to characterize cells and study neuronal circuits.

‘Perturb and record’ optogenetics probe aims precision spotlight at brain structures
The tool provides a new way to characterize cells and study neuronal circuits.
Inhibitory cells work in concert to orchestrate neuronal activity in mouse brain
A cubic millimeter of brain tissue, meticulously sectioned, stained and scrutinized over the past seven years, reveals in stunning detail the role of inhibitory interneurons in brain structure and function.

Inhibitory cells work in concert to orchestrate neuronal activity in mouse brain
A cubic millimeter of brain tissue, meticulously sectioned, stained and scrutinized over the past seven years, reveals in stunning detail the role of inhibitory interneurons in brain structure and function.
Organoids and assembloids offer a new window into human brain
These sophisticated 3D cultures reveal previously inaccessible stages of human brain development and enable the systematic study of disease genes.

Organoids and assembloids offer a new window into human brain
These sophisticated 3D cultures reveal previously inaccessible stages of human brain development and enable the systematic study of disease genes.
Claims of necessity and sufficiency are not well suited for the study of complex systems
The earliest studies on necessary and sufficient neural populations were performed on simple invertebrate circuits. Does this logic still serve us as we tackle more sophisticated outputs?

Claims of necessity and sufficiency are not well suited for the study of complex systems
The earliest studies on necessary and sufficient neural populations were performed on simple invertebrate circuits. Does this logic still serve us as we tackle more sophisticated outputs?
The Transmitter’s favorite podcasts of 2024
Our picks include a deep dive into dopamine, the role of PKMzeta in memory, and studying the stomatogastric ganglion.

The Transmitter’s favorite podcasts of 2024
Our picks include a deep dive into dopamine, the role of PKMzeta in memory, and studying the stomatogastric ganglion.
Novel neurons upend ‘yin-yang’ model of hunger, satiety in brain
The new type of leptin-sensitive cells curb hunger quickly—adding to an increasingly complex picture of brain circuits that control feeding behaviors.

Novel neurons upend ‘yin-yang’ model of hunger, satiety in brain
The new type of leptin-sensitive cells curb hunger quickly—adding to an increasingly complex picture of brain circuits that control feeding behaviors.
START method assembles brain’s wiring diagram by cell type
The new technique mapped the interactions of about 50 kinds of inhibitory neurons in the mouse visual cortex in finer detail than previous approaches.

START method assembles brain’s wiring diagram by cell type
The new technique mapped the interactions of about 50 kinds of inhibitory neurons in the mouse visual cortex in finer detail than previous approaches.
As circuits wire up, interneurons take cues from surrounding cells
The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.

As circuits wire up, interneurons take cues from surrounding cells
The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.
Male and female brains, Proust, and Catherine Dulac
The 2021 Breakthrough Prize winner explains how reading widely shaped her worldview, and discusses the vomeronasal organ.

Male and female brains, Proust, and Catherine Dulac
The 2021 Breakthrough Prize winner explains how reading widely shaped her worldview, and discusses the vomeronasal organ.
Explore more from The Transmitter
Oscar Ferrante, Rony Hirschhorn and Alex Lepauvre discuss putting integrated information and global neuronal workspace theories of consciousness to the test
The trio is part of the adversarial collaboration launched to test various theories of consciousness, a project known as COGITATE.
Oscar Ferrante, Rony Hirschhorn and Alex Lepauvre discuss putting integrated information and global neuronal workspace theories of consciousness to the test
The trio is part of the adversarial collaboration launched to test various theories of consciousness, a project known as COGITATE.
Sleep doesn’t just consolidate memories; it actively shapes them
The rapid eye movement (REM) phase preserves newly acquired memories, but deeper non-REM sleep helps to adapt and update them, according to “heroic” day-long electrode recordings in rats.

Sleep doesn’t just consolidate memories; it actively shapes them
The rapid eye movement (REM) phase preserves newly acquired memories, but deeper non-REM sleep helps to adapt and update them, according to “heroic” day-long electrode recordings in rats.
Altered translation in SYNGAP1-deficient mice; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 5 May.

Altered translation in SYNGAP1-deficient mice; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 5 May.