Neurotransmitters
Recent articles
New dopamine sensor powers three-color imaging in live animals
The tool leverages a previously unused segment of the color spectrum to track the neurotransmitter and can be used with two additional sensors to monitor other neurochemicals at different wavelengths.
New dopamine sensor powers three-color imaging in live animals
The tool leverages a previously unused segment of the color spectrum to track the neurotransmitter and can be used with two additional sensors to monitor other neurochemicals at different wavelengths.
‘Understudied secret’ in brain dampens nicotine drive in mice
The interpeduncular nucleus produces an aversion to nicotine, even at low doses, and helps moderate how rewarding mice find the drug.
‘Understudied secret’ in brain dampens nicotine drive in mice
The interpeduncular nucleus produces an aversion to nicotine, even at low doses, and helps moderate how rewarding mice find the drug.
Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.
Bespoke photometry system captures variety of dopamine signals in mice
The tool tracks the excitation of an engineered protein that senses dopamine’s absolute levels, including fast and slow fluctuations in real time, and offers new insights into how the signals change across the brain.
Timothy Ryan on his pivotal switch from studying particle physics to decoding synaptic transmission
Dissuaded from pursuing theoretical physics and deterred by the “long feedback loop” in experimental physics, the National Academy of Sciences member took inspiration from “polymath” Watt Webb and “visionary” Stephen Smith—and learned to work “completely outside his comfort zone.”
Timothy Ryan on his pivotal switch from studying particle physics to decoding synaptic transmission
Dissuaded from pursuing theoretical physics and deterred by the “long feedback loop” in experimental physics, the National Academy of Sciences member took inspiration from “polymath” Watt Webb and “visionary” Stephen Smith—and learned to work “completely outside his comfort zone.”
Biosensors and being fearless with Lin Tian
Tian discusses protein function and structure, and the historic city in China where she was born.
Biosensors and being fearless with Lin Tian
Tian discusses protein function and structure, and the historic city in China where she was born.
What happens when a histopathologist teams up with computational modelers?
Answers emerge in my chat with Nicola Palomero-Gallagher, a rare example of someone who connects the brain’s microscopic constituents and macroscopic features.
What happens when a histopathologist teams up with computational modelers?
Answers emerge in my chat with Nicola Palomero-Gallagher, a rare example of someone who connects the brain’s microscopic constituents and macroscopic features.
Abundant motor proteins disrupt cries in FOXP2 mice
Knocking down the gene that codes for the proteins normalizes the vocalizations.
Abundant motor proteins disrupt cries in FOXP2 mice
Knocking down the gene that codes for the proteins normalizes the vocalizations.
Autism and the cell’s antennae
Many autism-linked genes are somehow tied to cilia, the tiny hair-like sensors that stud a cell’s surface. But the question remains whether, and how, cilia differences contribute to the condition.
Autism and the cell’s antennae
Many autism-linked genes are somehow tied to cilia, the tiny hair-like sensors that stud a cell’s surface. But the question remains whether, and how, cilia differences contribute to the condition.
Multi-omics study captures CNTNAP2’s far-ranging effects
The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.
Multi-omics study captures CNTNAP2’s far-ranging effects
The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.
Tripping over the potential of psychedelics for autism
Drugs such as LSD act primarily on the serotonin system, which is implicated in autism — and some autistic people who experiment with psychoactive compounds report enhanced social connections, among other benefits. But researchers have more questions than answers.
Tripping over the potential of psychedelics for autism
Drugs such as LSD act primarily on the serotonin system, which is implicated in autism — and some autistic people who experiment with psychoactive compounds report enhanced social connections, among other benefits. But researchers have more questions than answers.
Explore more from The Transmitter
This paper changed my life: Abigail Person on birdsong, feed-forward circuits and convergent computations
By isolating specific neuron types involved in zebra finch birdsong, this 2002 Nature paper from Michael Fee and colleagues revealed elegant neural mechanisms controlling the timing of natural learned behavior.
This paper changed my life: Abigail Person on birdsong, feed-forward circuits and convergent computations
By isolating specific neuron types involved in zebra finch birdsong, this 2002 Nature paper from Michael Fee and colleagues revealed elegant neural mechanisms controlling the timing of natural learned behavior.
Prosocial effects of oxytocin are state dependent; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 11 August.
Prosocial effects of oxytocin are state dependent; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 11 August.
The challenge of defining a neural population
Our current approach is largely arbitrary. We need new methods for grouping cells, ideally by their dynamics.
The challenge of defining a neural population
Our current approach is largely arbitrary. We need new methods for grouping cells, ideally by their dynamics.