Jessica Mariani
Postdoctoral Associate
Child Study Center, Yale School of Medicine
From this contributor
Promise and pitfalls of induced stem cells for autism
Induced pluripotent stem cells, which have the ability to become any cell type, including neurons, offer a powerful way to study neuropsychiatric disorders. But for this approach to reach its full potential, researchers must first address several challenges, such as variability between cell lines, say Flora Vaccarino and Jessica Mariani.
Promise and pitfalls of induced stem cells for autism
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Nuclear location helps control gene activity during brain development
A study of developing human brain tissue suggests that genes switch on more strongly when they move from the nucleus’s edge toward structures that contain proteins involved in making and processing RNA.