Manifolds

Recent articles

Tatiana Engel explains how to connect high-dimensional neural circuitry with low-dimensional cognitive functions

Neuroscientists have long sought to understand the relationship between structure and function in the vast connectivity and activity patterns in the brain. Engel discusses her modeling approach to discovering the hidden patterns that connect the two.

By Paul Middlebrooks
3 December 2025 | 1 min read
Illustration of a colorful, donut-shaped object resting on a distorted plane with its own topography.

Neural manifolds: Latest buzzword or pathway to understand the brain?

When you cut away the misconceptions, neural manifolds present a conceptually appropriate level at which systems neuroscientists can study the brain.

By Matthew Perich
2 October 2024 | 8 min read

Explore more from The Transmitter

Mouse cortical organoid.

Hasty stem cells highlight potential limitation with cortical organoids

The models recapitulate many key developmental processes, but some radial glial cells in mouse organoids make neurons earlier than they should.

By Giorgia Guglielmi
22 September 2026 | 4 min read
Illustration of an open journal featuring lines of text and small illustrations of eyes and mouths.

Two populations of neurons, two effects on sociability; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 21 September.

By Jill Adams
22 September 2026 | 2 min read

Finding the Rett syndrome gene and ways to fix it

Kevin Mitchell talks with Huda Zoghbi about her work identifying the MECP2 gene, its role in the brain and therapies to address its dysfunction.

By Kevin Mitchell
21 September 2026 | 4 min read