Synaptic pruning

Recent articles

Research image of the mouse dentate gyrus.

Microglia implicated in infantile amnesia

The glial cells could explain the link between maternal immune activation and autism-like behaviors in mice.

By Lauren Schneider
12 February 2026 | 5 min read
Research image of neuronal proteins in mice.

Aging neurons outsource garbage disposal, clog microglia

Degradation-resistant proteins pass from neurons to glial cells in a process that may spread protein clumps around the brain, according to a study in mice.

By Holly Barker
10 February 2026 | 5 min read
Two panels depict different brain wiring-like networks.

Rethinking how neural activity sculpts critical periods

New findings on the role of neural activity in developing circuits are challenging our prior notions about the rules that govern critical periods.

By Gregg Wildenberg
3 June 2025 | 5 min read
Research image of retinal ganglion cells in the lateral geniculate nucleus in mice.

Microglia’s pruning function called into question

Scientists are divided over the extent to which the cells sculpt circuits during development.

By RJ Mackenzie
24 October 2024 | 9 min read

Explore more from The Transmitter

Research figure of fly neurons transforming taste information into movements.

Fly taste connectome traces paths from sensation to action

The map—the first of its kind for an animal more complex than Caenorhabditis elegans—gives neuroscientists a trove of testable hypotheses about how neuronal circuits guide feeding behaviors.

By Lauren Schenkman
30 October 2026 | 5 min read
Gerry Fischbach at a podium.

Remembering Gerry Fischbach, ‘orchestra conductor’ who brought scientists together

Fischbach, who died 25 October, elucidated the dynamic changes in neuromuscular junctions. Beyond the lab, he shaped careers, academic departments and scientific societies.

By Claudia López Lloreda
29 October 2026 | 8 min read
Mouse wearing a white, cube-like device on its head.

WILD platform levels up ability to record brain activity, behavior in nature

The customizable rig combines multimodal recording, onboard processing and neuronal manipulation to power more complex experiments.

By Simon Makin
29 October 2026 | 6 min read