Maria Karayiorgou
Professor
Columbia University
From this contributor
Dosage effects of 22q11 chromosomal region
Research into the 22q11.2 chromosomal region, which is linked to both schizophrenia and autism, can provide important insights into how rare duplications and deletions may lead to neuropsychiatric disorders, says Maria Karayiorgou.
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The United States and Europe are dedicating hundreds of millions of dollars in funding to advance novel alternative methods, but not all neuroscientists see this as a positive step.
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Trainees need to learn how to identify a neuroscience paper’s major takeaways and integrate them into their understanding. This skill doesn’t come from outsourcing the work to large language models.
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Head direction cells stably orient mice to outside world
The cells’ representations show little drift over time—unlike those of other navigation system neurons—and may provide a “rigid backbone” for more flexible sensory and cognitive responses.