CRISPR
Recent articles
Cell ‘antennae’ link autism, congenital heart disease
Variants in genes tied to both conditions derail the formation of cilia, the tiny hair-like structure found on almost every cell in the body, a new study finds.
Cell ‘antennae’ link autism, congenital heart disease
Variants in genes tied to both conditions derail the formation of cilia, the tiny hair-like structure found on almost every cell in the body, a new study finds.
Opioid receptors may guide formation of gut nervous system in zebrafish
Fish lacking functional copies of the receptors have fewer enteric neurons than usual, but the findings await further validation.
Opioid receptors may guide formation of gut nervous system in zebrafish
Fish lacking functional copies of the receptors have fewer enteric neurons than usual, but the findings await further validation.
CRISPR gives autism-linked genes a boost, rescues functioning
A modified form of the gene-editing tool increases the expression of CHD8 and SCN2A, showing potential for autism therapies.
CRISPR gives autism-linked genes a boost, rescues functioning
A modified form of the gene-editing tool increases the expression of CHD8 and SCN2A, showing potential for autism therapies.
Cocaine, morphine commandeer neurons normally activated by food, water in mice
Confirming a long-held hypothesis, repeated exposure to the drugs alters neurons in the nucleus accumbens, the brain’s reward center, and curbs an animal’s urge for sustenance.
Cocaine, morphine commandeer neurons normally activated by food, water in mice
Confirming a long-held hypothesis, repeated exposure to the drugs alters neurons in the nucleus accumbens, the brain’s reward center, and curbs an animal’s urge for sustenance.
New RNA editor boasts increased versatility, safety
The “PRECISE” technique reprograms cells in a way that, unlike DNA editors, avoids potentially permanent off-target effects.
New RNA editor boasts increased versatility, safety
The “PRECISE” technique reprograms cells in a way that, unlike DNA editors, avoids potentially permanent off-target effects.
Mutation in top autism-linked gene may alter eye reflex
The discovery could help clinicians diagnose children who carry mutations in the gene, called SCN2A, and gauge their responses to potential therapies.
Mutation in top autism-linked gene may alter eye reflex
The discovery could help clinicians diagnose children who carry mutations in the gene, called SCN2A, and gauge their responses to potential therapies.
New template streamlines sharing clinical trial results
This month’s Going on Trial newsletter explores a new tool for communicating with clinical trial participants and their families, among other drug development news.
New template streamlines sharing clinical trial results
This month’s Going on Trial newsletter explores a new tool for communicating with clinical trial participants and their families, among other drug development news.
Method pinpoints cell-specific effects of autism-linked mutations
The approach, which combines CRISPR with single-cell analyses of organoids, suggests that intermediate progenitor cells are especially vulnerable to mutations associated with autism.
Method pinpoints cell-specific effects of autism-linked mutations
The approach, which combines CRISPR with single-cell analyses of organoids, suggests that intermediate progenitor cells are especially vulnerable to mutations associated with autism.
Compact kin of CRISPR discovered across eukaryotes
The newfound DNA-cutting enzyme, called Fanzor, can be programmed to edit the human genome and could prove easier to deliver to cells than current CRISPR tools.
Compact kin of CRISPR discovered across eukaryotes
The newfound DNA-cutting enzyme, called Fanzor, can be programmed to edit the human genome and could prove easier to deliver to cells than current CRISPR tools.
Latest ‘prime-editing’ tools tackle delivery, safety issues
The gene-editing advances make it easier to target specific tissues in mice and detect off-target effects.
Latest ‘prime-editing’ tools tackle delivery, safety issues
The gene-editing advances make it easier to target specific tissues in mice and detect off-target effects.
Explore more from The Transmitter
This paper changed my life: Dan Goodman on a paper that reignited the field of spiking neural networks
Friedemann Zenke’s 2019 paper, and its related coding tutorial SpyTorch, made it possible to apply modern machine learning to spiking neural networks. The innovation reinvigorated the field.
This paper changed my life: Dan Goodman on a paper that reignited the field of spiking neural networks
Friedemann Zenke’s 2019 paper, and its related coding tutorial SpyTorch, made it possible to apply modern machine learning to spiking neural networks. The innovation reinvigorated the field.
Autism and anxiety insights; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 15 September.
Autism and anxiety insights; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 15 September.
First nerve-net connectome shows how evolutionarily ancient nervous system coordinates movement
The map of a comb jelly’s aboral nerve net, which helps the animal orient and position itself within the water column, reveals a unique system for sensing the world and coordinating movement.
First nerve-net connectome shows how evolutionarily ancient nervous system coordinates movement
The map of a comb jelly’s aboral nerve net, which helps the animal orient and position itself within the water column, reveals a unique system for sensing the world and coordinating movement.