CRISPR

Recent articles

Headshots of Yale researchers Yong-Hui Jiang and Jiangbing Zhou.

Supported by a $40 million NIH grant, Yale brain shuttle technology raises questions

Yale University claims its STEP platform might be able to deliver gene-editing tools into the brain via multiple routes. Researchers are eager to see more.

By Natalia Mesa
3 June 2026 | 11 min read
Illustration of spiny mouse.

Learning why spiny mice play well with others

Aubrey Kelly studies the gregarious mammal to explore how the brain controls complex social behaviors “akin to friendship.”

By Hannah Thomasy
2 June 2026 | 5 min read
DNA helix.

Advances in genetic medicine took center stage at INSAR

The president of the Autism Science Foundation and parent of a child with profound autism reflects on how advances in the treatment of rare gene variants bring hope to many families.

By Alison Singer
5 May 2026 | 4 min read
Research image of zebrafish brain activity.

Nearly 400 compounds affect behaviors tied to autism-linked genes in zebrafish

Estropipate, paclitaxel and levocarnitine altered behaviors tied to SCN2A and DYRK1A variants specifically, a new open-source platform revealed.

By Charles Q. Choi
16 April 2026 | 4 min read
Research image of SCN2A neurons.

Boosting SCN2A expression reduces seizures in mice

A modified form of CRISPR amps up expression of the gene—a strategy that could apply to other gene variations linked to autism.

By Charles Q. Choi
9 October 2025 | 5 min read

Cell ‘antennae’ link autism, congenital heart disease

Variants in genes tied to both conditions derail the formation of cilia, the tiny hair-like structure found on almost every cell in the body, a new study finds.

By Lauren Schenkman
24 July 2025 | 0 min watch
Research image of enteric neurons in zebrafish.

Opioid receptors may guide formation of gut nervous system in zebrafish

Fish lacking functional copies of the receptors have fewer enteric neurons than usual, but the findings await further validation.

By Olivia Gieger
26 June 2024 | 4 min read
Research image of two fluorescent-stained organoids.

CRISPR gives autism-linked genes a boost, rescues functioning

A modified form of the gene-editing tool increases the expression of CHD8 and SCN2A, showing potential for autism therapies.

By Giorgia Guglielmi
23 May 2024 | 5 min read
A diagram of green neurnons

Cocaine, morphine commandeer neurons normally activated by food, water in mice

Confirming a long-held hypothesis, repeated exposure to the drugs alters neurons in the nucleus accumbens, the brain’s reward center, and curbs an animal’s urge for sustenance.

By Lauren Schenkman
8 May 2024 | 5 min read
A digital rendering of a strand of RNA

New RNA editor boasts increased versatility, safety

The “PRECISE” technique reprograms cells in a way that, unlike DNA editors, avoids potentially permanent off-target effects.

By Charles Q. Choi
11 April 2024 | 4 min read

Explore more from The Transmitter

Illustration of a bridge shaped like minds.

Commentary: Citation graphs may underestimate neuroscience’s influence on AI

An alternative, albeit less quantitative, way to trace this history is through the people who carried ideas between the fields.

By Anthony Zador
26 October 2026 | 5 min read
Illustration of a person, shown from the torso down, walking over a bridge shaped like minds.

Commentary: The rising absolute number of neuro-inspired AI papers represents a substantial footprint

Many of the design choices present in the current generation of artificial-intelligence tools parallel purported properties of the brain.

By Kim Stachenfeld
26 October 2026 | 2 min read
Illustration of a person walking over a bridge shaped like minds.

Examining the bridge between neuroscience and AI

A citation analysis reveals that the connection between the two fields is real and gaining momentum. But it’s also narrow and tool-heavy; we need to find ways to widen it.

By Renato Duarte
26 October 2026 | 12 min read