CRISPR

Recent articles

Cell ‘antennae’ link autism, congenital heart disease

Variants in genes tied to both conditions derail the formation of cilia, the tiny hair-like structure found on almost every cell in the body, a new study finds.

By Lauren Schenkman
24 July 2025 | 4 min listen
Research image of enteric neurons in zebrafish.

Opioid receptors may guide formation of gut nervous system in zebrafish

Fish lacking functional copies of the receptors have fewer enteric neurons than usual, but the findings await further validation.

By Olivia Gieger
26 June 2024 | 4 min read
Research image of two fluorescent-stained organoids.

CRISPR gives autism-linked genes a boost, rescues functioning

A modified form of the gene-editing tool increases the expression of CHD8 and SCN2A, showing potential for autism therapies.

By Giorgia Guglielmi
23 May 2024 | 5 min read
A diagram of green neurnons

Cocaine, morphine commandeer neurons normally activated by food, water in mice

Confirming a long-held hypothesis, repeated exposure to the drugs alters neurons in the nucleus accumbens, the brain’s reward center, and curbs an animal’s urge for sustenance.

By Lauren Schenkman
8 May 2024 | 5 min read
A digital rendering of a strand of RNA

New RNA editor boasts increased versatility, safety

The “PRECISE” technique reprograms cells in a way that, unlike DNA editors, avoids potentially permanent off-target effects.

By Charles Q. Choi
11 April 2024 | 4 min read
A slice of a cerebellum.

Mutation in top autism-linked gene may alter eye reflex

The discovery could help clinicians diagnose children who carry mutations in the gene, called SCN2A, and gauge their responses to potential therapies.

By Charles Q. Choi
26 February 2024 | 5 min read
Illustration of a sheet of red and white pills, with the red pills arranged in the form of a question mark.

New template streamlines sharing clinical trial results

This month’s Going on Trial newsletter explores a new tool for communicating with clinical trial participants and their families, among other drug development news.

By Calli McMurray
31 October 2023 | 7 min read
Research image of cerebral organoids.

Method pinpoints cell-specific effects of autism-linked mutations

The approach, which combines CRISPR with single-cell analyses of organoids, suggests that intermediate progenitor cells are especially vulnerable to mutations associated with autism.

By Celia Ford
3 October 2023 | 3 min read
Research images of a Fanzor protein.

Compact kin of CRISPR discovered across eukaryotes

The newfound DNA-cutting enzyme, called Fanzor, can be programmed to edit the human genome and could prove easier to deliver to cells than current CRISPR tools.

By Charles Q. Choi
31 July 2023 | 5 min read
Research image of gene-edited mouse liver cells compared to controls.

Latest ‘prime-editing’ tools tackle delivery, safety issues

The gene-editing advances make it easier to target specific tissues in mice and detect off-target effects.

By Charles Q. Choi
27 June 2023 | 5 min read

Explore more from The Transmitter

Emotion research has a communication conundrum

In 2025, the words we use to describe emotions matter, but their definitions are controversial. Here, I unpack the different positions in this space and the rationales behind them—and I invite 13 experts to chime in.

By Nicole Rust
5 September 2025 | 37 min listen

Autism-linked copy number variants always boost autism likelihood

By contrast, varied doses of the same genes decrease or increase the odds of five other conditions, with distinct biological consequences, two new preprints show.

By Natalia Mesa
4 September 2025 | 7 min listen

Everything everywhere all at once: Decision-making signals engage entire brain

The findings, gleaned from the most comprehensive map yet of brain activity during decision-making in mice, show that the process is even more distributed than previously thought.

By Claudia López Lloreda
3 September 2025 | 5 min read

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