Modeling

Recent articles

Composite of Autism Data Science Initiative researcher headshots.

Meet the Autism Data Science Initiative grantees

The awarded projects plan to study gene-and-environment interactions in people, stem cells and organoids, as well as predictors of positive life outcomes in autistic youth and adults.

By Calli McMurray
3 October 2025 | 2 min read
Research image of neuron organization in c elegans.

Worms help untangle brain structure/function mystery

The synaptic connectome of most animals bears little resemblance to functional brain maps, but it can still predict neuronal activity, according to two preprints that tackle the puzzle in C. elegans

By Holly Barker
29 August 2025 | 9 min listen
Computer-generated illustration of a brain in a broken jar.

Breaking the jar: Why NeuroAI needs embodiment

Brain function is inexorably shaped by the body. Embracing this fact will benefit computational models of real brain function, as well as the design of artificial neural networks.

By Bing Wen Brunton, John Tuthill
21 July 2025 | 11 min listen
Research image of mouse brain slices.

Some dopamine neurons signal default behaviors to reinforce habits

Movement-sensing neurons that target the striatum influence a mouse’s choice of action by favoring routine.

By Holly Barker
11 June 2025 | 5 min listen
Illustration of synapse-like threads connecting in various ways.

Learning in living mice defies classic synaptic plasticity rule

Donald Hebb’s theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment, according to a new study.

By Sydney Wyatt
28 May 2025 | 6 min listen

Escaping groupthink: What animals’ behavioral quirks reveal about the brain

Neuroscientists have long ignored the variability in animals’ behavioral responses in favor of studying differences across groups. But work on the brain differences that underlie that variability is beginning to pay off.

By Angie Voyles Askham
23 May 2025 | 10 min listen
Tic-tac-toe board with pills representing x’s and o’s.

Basic pain research ‘is not working’: Q&A with Steven Prescott and Stéphanie Ratté

Prescott and Ratté critique the clinical relevance of preclinical studies in the field and highlight areas for improvement.

By Sydney Wyatt
18 April 2025 | 7 min read

Gabriele Scheler reflects on the interplay between language, thought and AI

She discusses how verbal thought shapes cognition, why inner speech is foundational to human intelligence and what current artificial-intelligence models get wrong about language.

By Paul Middlebrooks
26 March 2025 | 96 min listen
Illustrated portrait of Kanaka Rajan.

How neuroscience comics add KA-POW! to the field: Q&A with Kanaka Rajan

The artistic approach can help explain complex ideas frame by frame without diluting the science, Rajan says.

By Olivia Gieger
9 October 2024 | 7 min read
Illustration of hands sewing red and white threads in a DNA-like pattern into a blue-gray fabric.

Untangling biological threads from autism’s phenotypic patchwork reveals four core subtypes

People belonging to the same subtype share genetic variants, behaviors and often co-occurring diagnoses, according to a new preprint.

By Holly Barker
3 October 2024 | 5 min read

Explore more from The Transmitter

Illustration of a neuron.

New questions around motor neurons and plasticity

A researcher’s theory hangs muscle degeneration on a broken neural circuit.

By David Adam
10 October 2025 | 11 min listen
Research image of SCN2A neurons.

Boosting SCN2A expression reduces seizures in mice

A modified form of CRISPR amps up expression of the gene—a strategy that could apply to other gene variations linked to autism.

By Charles Q. Choi
9 October 2025 | 5 min read

Nikolay Kukushkin discusses his book, ‘One Hand Clapping: Unraveling the Mystery of the Human Mind’

He explains how meaning arises in the interactions found throughout nature and evolution, from molecules to minds.

By Paul Middlebrooks
8 October 2025 | 1 min read

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