Modeling
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Meet the Autism Data Science Initiative grantees
The awarded projects plan to study gene-and-environment interactions in people, stem cells and organoids, as well as predictors of positive life outcomes in autistic youth and adults.

Meet the Autism Data Science Initiative grantees
The awarded projects plan to study gene-and-environment interactions in people, stem cells and organoids, as well as predictors of positive life outcomes in autistic youth and adults.
Worms help untangle brain structure/function mystery
The synaptic connectome of most animals bears little resemblance to functional brain maps, but it can still predict neuronal activity, according to two preprints that tackle the puzzle in C. elegans.

Worms help untangle brain structure/function mystery
The synaptic connectome of most animals bears little resemblance to functional brain maps, but it can still predict neuronal activity, according to two preprints that tackle the puzzle in C. elegans.
Breaking the jar: Why NeuroAI needs embodiment
Brain function is inexorably shaped by the body. Embracing this fact will benefit computational models of real brain function, as well as the design of artificial neural networks.

Breaking the jar: Why NeuroAI needs embodiment
Brain function is inexorably shaped by the body. Embracing this fact will benefit computational models of real brain function, as well as the design of artificial neural networks.
Some dopamine neurons signal default behaviors to reinforce habits
Movement-sensing neurons that target the striatum influence a mouse’s choice of action by favoring routine.

Some dopamine neurons signal default behaviors to reinforce habits
Movement-sensing neurons that target the striatum influence a mouse’s choice of action by favoring routine.
Learning in living mice defies classic synaptic plasticity rule
Donald Hebb’s theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment, according to a new study.

Learning in living mice defies classic synaptic plasticity rule
Donald Hebb’s theory—memorably summarized as “cells that fire together, wire together”—does not explain the shifting hippocampal connections in mice learning to navigate a virtual environment, according to a new study.
Escaping groupthink: What animals’ behavioral quirks reveal about the brain
Neuroscientists have long ignored the variability in animals’ behavioral responses in favor of studying differences across groups. But work on the brain differences that underlie that variability is beginning to pay off.
Escaping groupthink: What animals’ behavioral quirks reveal about the brain
Neuroscientists have long ignored the variability in animals’ behavioral responses in favor of studying differences across groups. But work on the brain differences that underlie that variability is beginning to pay off.
Basic pain research ‘is not working’: Q&A with Steven Prescott and Stéphanie Ratté
Prescott and Ratté critique the clinical relevance of preclinical studies in the field and highlight areas for improvement.

Basic pain research ‘is not working’: Q&A with Steven Prescott and Stéphanie Ratté
Prescott and Ratté critique the clinical relevance of preclinical studies in the field and highlight areas for improvement.
Gabriele Scheler reflects on the interplay between language, thought and AI
She discusses how verbal thought shapes cognition, why inner speech is foundational to human intelligence and what current artificial-intelligence models get wrong about language.
Gabriele Scheler reflects on the interplay between language, thought and AI
She discusses how verbal thought shapes cognition, why inner speech is foundational to human intelligence and what current artificial-intelligence models get wrong about language.
How neuroscience comics add KA-POW! to the field: Q&A with Kanaka Rajan
The artistic approach can help explain complex ideas frame by frame without diluting the science, Rajan says.

How neuroscience comics add KA-POW! to the field: Q&A with Kanaka Rajan
The artistic approach can help explain complex ideas frame by frame without diluting the science, Rajan says.
Untangling biological threads from autism’s phenotypic patchwork reveals four core subtypes
People belonging to the same subtype share genetic variants, behaviors and often co-occurring diagnoses, according to a new preprint.

Untangling biological threads from autism’s phenotypic patchwork reveals four core subtypes
People belonging to the same subtype share genetic variants, behaviors and often co-occurring diagnoses, according to a new preprint.
Explore more from The Transmitter
New questions around motor neurons and plasticity
A researcher’s theory hangs muscle degeneration on a broken neural circuit.

New questions around motor neurons and plasticity
A researcher’s theory hangs muscle degeneration on a broken neural circuit.
Boosting SCN2A expression reduces seizures in mice
A modified form of CRISPR amps up expression of the gene—a strategy that could apply to other gene variations linked to autism.

Boosting SCN2A expression reduces seizures in mice
A modified form of CRISPR amps up expression of the gene—a strategy that could apply to other gene variations linked to autism.
Nikolay Kukushkin discusses his book, ‘One Hand Clapping: Unraveling the Mystery of the Human Mind’
He explains how meaning arises in the interactions found throughout nature and evolution, from molecules to minds.
Nikolay Kukushkin discusses his book, ‘One Hand Clapping: Unraveling the Mystery of the Human Mind’
He explains how meaning arises in the interactions found throughout nature and evolution, from molecules to minds.