Excitability

Recent articles

Research image of mouse brain slices stained in red and blue.

Ramping up cortical activity in early life sparks autism-like behaviors in mice

The findings add fuel to the long-running debate over how an imbalance in excitatory and inhibitory signaling contributes to the autism.

By Sarah DeWeerdt
30 October 2025 | 6 min read
Research image of different interneuron subtypes responding to the absence of pyramidal neurons in the mouse cortex.

As circuits wire up, interneurons take cues from surrounding cells

The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.

By Olivia Gieger
14 August 2024 | 5 min read
A research image of neuronal dendrites in mice.

Top autism-linked genes join forces to shape synaptic plasticity

The protein products of ANK2 and SCN2A interact to regulate dendritic excitability.

By Holly Barker
29 January 2024 | 4 min read

Explore more from The Transmitter

Research image of perineuronal nets.

Organoids missing the TSC2 gene form rogue astrocytes; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 28 September.

By Jill Adams
29 September 2026 | 2 min read
Research diagram of task-aligned activity rasters.

Cerebellar neurons reorient brain activity to differentiate similar behaviors

The findings provide a new perspective on how granule cells help to generalize learning across tasks.

By Holly Barker
29 September 2026 | 4 min read
Illustration of waterfall inside a woman's brain.

Revisiting the neural correlates of consciousness

Life happens in real time, but experience may be composed in ragtime—like the music genre, full of offbeat notes and uneven rhythms. The assumption that waking life consists of a “stream” of conscious representations has inadvertently led consciousness science to its current impasse.

By Francis T. Fallon, Michael Pitts
28 September 2026 | 7 min read