Excitability

Recent articles

Research image of mouse brain slices stained in red and blue.

Ramping up cortical activity in early life sparks autism-like behaviors in mice

The findings add fuel to the long-running debate over how an imbalance in excitatory and inhibitory signaling contributes to the autism.

By Sarah DeWeerdt
30 October 2025 | 6 min read
Research image of different interneuron subtypes responding to the absence of pyramidal neurons in the mouse cortex.

As circuits wire up, interneurons take cues from surrounding cells

The inhibitory cells’ development, diversity and abundance in the cortex is directed in part by pyramidal cells, a new preprint suggests.

By Olivia Gieger
14 August 2024 | 5 min read
A research image of neuronal dendrites in mice.

Top autism-linked genes join forces to shape synaptic plasticity

The protein products of ANK2 and SCN2A interact to regulate dendritic excitability.

By Holly Barker
29 January 2024 | 4 min read

Explore more from The Transmitter

Fruit flies use memory to track odors

When flies encounter a tasty smell, they stroll in and out of the odor plume—a process that depends on encoding a memory of the angle needed to travel back to the plume, according to a new study.

By Calli McMurray
8 September 2026 | 2 min watch
Map of genome variation.

New methods to contextualize autism-linked genes, and more

Here is a roundup of autism-related news and research spotted around the web for the week of 7 September.

By Jill Adams
8 September 2026 | 2 min read
Illustration of folded origami.

Dimensionality—neuroscience’s red herring?

Placing too much emphasis on a specific interpretation of dimensionality, or treating it as an end-all quantification of some aspect of neural computation, may hinder progress in understanding the brain.

By Matthew Perich
7 September 2026 | 8 min read