Methylation
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Five-year-old human brain organoids aged on schedule
The cultured spheres typically mimic only prenatal development, but the five-year-old ones grown in Paola Arlotta’s lab acquired postnatal features.
Five-year-old human brain organoids aged on schedule
The cultured spheres typically mimic only prenatal development, but the five-year-old ones grown in Paola Arlotta’s lab acquired postnatal features.
Unknown isoform adds twist to theory of fragile X origins
Contrary to conventional wisdom, most people with fragile X syndrome express the FMR1 gene — albeit improperly.
Unknown isoform adds twist to theory of fragile X origins
Contrary to conventional wisdom, most people with fragile X syndrome express the FMR1 gene — albeit improperly.
New gene-editing method flags fragile X mutation for repair
The approach prompts cultured cells to correct the genetic mutation in fragile X syndrome using their own DNA repair system, but it still needs to be tested further.
New gene-editing method flags fragile X mutation for repair
The approach prompts cultured cells to correct the genetic mutation in fragile X syndrome using their own DNA repair system, but it still needs to be tested further.
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The relationship between structure and function in cortical networks
Michael Reimann explains how the shape of neurons puts strong constraints on how they are wired in a network, and how this affects their structure-function relationships.
The relationship between structure and function in cortical networks
Michael Reimann explains how the shape of neurons puts strong constraints on how they are wired in a network, and how this affects their structure-function relationships.
How brains prevent ‘catastrophic forgetting’
Dendrite-specific inhibition lets overlapping neuronal assemblies form across brain areas without erasing existing memories, a new modeling study suggests.
How brains prevent ‘catastrophic forgetting’
Dendrite-specific inhibition lets overlapping neuronal assemblies form across brain areas without erasing existing memories, a new modeling study suggests.
Lipids enter brain mapping limelight
Two new studies, including the first whole-brain lipid atlas in mice, uncover unforeseen complexity and influence during pregnancy and aging.
Lipids enter brain mapping limelight
Two new studies, including the first whole-brain lipid atlas in mice, uncover unforeseen complexity and influence during pregnancy and aging.