Rare variants
Recent articles
NeuroDev study maps previously unseen genetic variation in Africa
The project is helping to fill critical gaps in the genetic underpinnings of autism and other neurodevelopmental conditions.
NeuroDev study maps previously unseen genetic variation in Africa
The project is helping to fill critical gaps in the genetic underpinnings of autism and other neurodevelopmental conditions.
Revised statistical bar extracts less-common variants from autism genetics studies
Adjusting genetic analyses could help plug autism’s heritability gap, according to a new preprint.
Revised statistical bar extracts less-common variants from autism genetics studies
Adjusting genetic analyses could help plug autism’s heritability gap, according to a new preprint.
Common and rare variants shape distinct genetic architecture of autism in African Americans
Certain gene variants may have greater weight in determining autism likelihood for some populations, a new study shows.
Common and rare variants shape distinct genetic architecture of autism in African Americans
Certain gene variants may have greater weight in determining autism likelihood for some populations, a new study shows.
Sequencing study spotlights tight web of genes tied to autism
The findings, shared in a preprint, help to illuminate how a large and heterogeneous group of genes could be involved in autism.
Sequencing study spotlights tight web of genes tied to autism
The findings, shared in a preprint, help to illuminate how a large and heterogeneous group of genes could be involved in autism.
X marks the spot in search for autism variants
Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.
X marks the spot in search for autism variants
Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.
Many autism-linked proteins influence hair-like cilia on human brain cells
The finding may help explain autism’s association with multiple co-occurring conditions that involve cilia defects.
Many autism-linked proteins influence hair-like cilia on human brain cells
The finding may help explain autism’s association with multiple co-occurring conditions that involve cilia defects.
Untangling biological threads from autism’s phenotypic patchwork reveals four core subtypes
People belonging to the same subtype share genetic variants, behaviors and often co-occurring diagnoses, according to a new preprint.
Untangling biological threads from autism’s phenotypic patchwork reveals four core subtypes
People belonging to the same subtype share genetic variants, behaviors and often co-occurring diagnoses, according to a new preprint.
A genetics-first clinic for catching developmental conditions early: Q&A with Jacob Vorstman
A new clinic is assessing children who have a genetic predisposition for autism and other neurodevelopmental conditions—sometimes before traits appear.
A genetics-first clinic for catching developmental conditions early: Q&A with Jacob Vorstman
A new clinic is assessing children who have a genetic predisposition for autism and other neurodevelopmental conditions—sometimes before traits appear.
Giant analysis reveals how autism-linked genes affect brain cell types
Genes that predispose people to autism account for a large portion of the neuronal and glial cell changes seen in those with the condition.
Giant analysis reveals how autism-linked genes affect brain cell types
Genes that predispose people to autism account for a large portion of the neuronal and glial cell changes seen in those with the condition.
Genome structure could be key factor in some forms of autism
Variants in DNA stretches that do not code for proteins may alter the genome’s 3D architecture, influencing the expression of distant genes linked to autism.
Genome structure could be key factor in some forms of autism
Variants in DNA stretches that do not code for proteins may alter the genome’s 3D architecture, influencing the expression of distant genes linked to autism.
Explore more from The Transmitter
Amid funding uncertainty, neuroscientists report a mix of cynicism, persistence
Two years into one of the most tumultuous tenures in U.S. federal funding, researchers outline how they are coping with ongoing changes and reflect on the impact these changes are having on the system more broadly.
Amid funding uncertainty, neuroscientists report a mix of cynicism, persistence
Two years into one of the most tumultuous tenures in U.S. federal funding, researchers outline how they are coping with ongoing changes and reflect on the impact these changes are having on the system more broadly.
Reimagining Mexico’s brain bank
Since Alzheimer’s disease researcher José Luna-Muñoz assumed leadership of the facility—Latin America’s oldest—in 2011, he has been acquiring additional tissue types and is working to expand donor recruitment to rural areas.
Reimagining Mexico’s brain bank
Since Alzheimer’s disease researcher José Luna-Muñoz assumed leadership of the facility—Latin America’s oldest—in 2011, he has been acquiring additional tissue types and is working to expand donor recruitment to rural areas.
Revealing how crabs make their escape
Houdini-like Neohelice granulata offers a rare opportunity to record intracellularly from awake, behaving animals.
Revealing how crabs make their escape
Houdini-like Neohelice granulata offers a rare opportunity to record intracellularly from awake, behaving animals.