Huntington’s disease

Recent articles

Research image of brain cells involved with Amyotrophic lateral sclerosis (ALS) illuminated through genetic tools

Allen Institute sets sights on treatments for five brain diseases

The Brain Health Accelerator program aims to harness single-cell transcriptomics and cell-type-specific genetic tools to develop treatments for Alzheimer’s, Huntington’s and Parkinson’s diseases, Lewy body dementia and ALS.

By Calli McMurray
2 June 2026 | 5 min read
A repeated DNA strand extends farther from the left side of the image with each iteration.

Huntington’s disease gene variants past a certain size poison select cells

The findings—providing “the next step in the whole pathway”—help explain the disease’s late onset and offer hope that it has an extended therapeutic window.

By Angie Voyles Askham
16 January 2025 | 6 min read

Explore more from The Transmitter

Neuronal genes SATB2 and MEF2C.

Nuclear location helps control gene activity during brain development

A study of developing human brain tissue suggests that genes switch on more strongly when they move from the nucleus’s edge toward structures that contain proteins involved in making and processing RNA.

By Giorgia Guglielmi
20 August 2026 | 4 min read
Cortical organoids.

Five-year-old human brain organoids aged on schedule

The cultured spheres typically mimic only prenatal development, but the five-year-old ones grown in Paola Arlotta’s lab acquired postnatal features.

By Claudia López Lloreda
19 August 2026 | 5 min read