Huntington’s disease

Recent articles

Research image of brain cells involved with Amyotrophic lateral sclerosis (ALS) illuminated through genetic tools

Allen Institute sets sights on treatments for five brain diseases

The Brain Health Accelerator program aims to harness single-cell transcriptomics and cell-type-specific genetic tools to develop treatments for Alzheimer’s, Huntington’s and Parkinson’s diseases, Lewy body dementia and ALS.

By Calli McMurray
2 June 2026 | 5 min read
A repeated DNA strand extends farther from the left side of the image with each iteration.

Huntington’s disease gene variants past a certain size poison select cells

The findings—providing “the next step in the whole pathway”—help explain the disease’s late onset and offer hope that it has an extended therapeutic window.

By Angie Voyles Askham
16 January 2025 | 6 min read

Explore more from The Transmitter

Illustration of cake with genetic code inside.

The genome offers a recipe, not a blueprint, for the brain

During brain development, genes set the rules and turn the knobs; self-organization does much of the rest.

By Ila Fiete
2 November 2026 | 8 min read
Illustration of four faces of a rhesus macaque transitioning from opaque to transparent.

Autism research involving monkeys contends with uphill battle

Macaques and marmosets recapitulate the condition’s core traits better than mice can, but funding uncertainty and challenges at primate centers in the United States could make this work difficult to continue.

By Diana Kwon
2 November 2026 | 8 min read
A measuring cup with a whirlpool in it.

When is self-organization a mechanism in brain development?

Retinal waves offer a powerful example of a self-organizing system that can build structure without external guidance. The field would do well to embrace such phenomena more broadly as a type of mechanistic explanation.

By P. Robin Hiesinger
2 November 2026 | 6 min read