Huntington’s disease

Recent articles

Research image of brain cells involved with Amyotrophic lateral sclerosis (ALS) illuminated through genetic tools

Allen Institute sets sights on treatments for five brain diseases

The Brain Health Accelerator program aims to harness single-cell transcriptomics and cell-type-specific genetic tools to develop treatments for Alzheimer’s, Huntington’s and Parkinson’s diseases, Lewy body dementia and ALS.

By Calli McMurray
2 June 2026 | 5 min read
A repeated DNA strand extends farther from the left side of the image with each iteration.

Huntington’s disease gene variants past a certain size poison select cells

The findings—providing “the next step in the whole pathway”—help explain the disease’s late onset and offer hope that it has an extended therapeutic window.

By Angie Voyles Askham
16 January 2025 | 6 min read

Explore more from The Transmitter

Cortical organoids from the anterior (green) or posterior (red) cortex.

Polarized cortical organoids mimic the brain’s regional organization

The organoids show region-specific gene-expression changes that match those observed during fetal development.

By Holly Barker
24 September 2026 | 4 min read
Research diagram of gene expression.

Prefrontal cortex has three transcriptomic acts across human lifespan, new atlas suggests

Various genes show distinct exits and entrances with age in the open-source dataset, the largest of its kind to date.

By Siddhant Pusdekar
23 September 2026 | 5 min read

Microglia scoop out garbage from inside neurons

Through a newly identified process called skoupocytosis, neurons recruit the immune cells to remove cellular waste they find hard to deal with themselves.

By Siddhant Pusdekar
23 September 2026 | 0 min watch