Multiplex families

Recent articles

Two infants.

Cousin comparison parses genetic effects in autism

The approach helps reveal whether maternal genes contribute directly to autism in children or have indirect effects on the prenatal environment.

By Charles Q. Choi
18 June 2026 | 4 min read
Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results.

Null and Noteworthy: Modified MRI; father findings

This month’s newsletter tackles null findings from an attempted replication of a “revolutionary” MRI approach and an analysis of family genetics.

By Emily Harris
22 June 2023 | 4 min read
An illustration of doctors examining a larger-than-life DNA strand

Whole-genome trove ties new genes, variants to autism

A massive update to the MSSNG dataset gives qualified researchers ready access to explore autism’s genetic architecture on a cloud-based platform.

By Isabel Ruehl
12 December 2022 | 4 min read
Abstraction of human genome data with some sections circled.

Analysis ups estimate of spontaneous mutations’ role in autism

Spontaneous genetic mutations contribute to autism in 30 to 39 percent of all people with the condition, and 52 to 67 percent of autistic children whose siblings do not also have the condition.

By Laura Dattaro
27 September 2021 | 5 min read

Ultra-rare variants point to new autism candidate genes

A large, whole-genome sequencing study of families yields insights into ultra-rare genetic variants that contribute to autism.

By Niko McCarty
26 July 2021 | 4 min read
Paper DNA with one torn base to signify a point mutation.

Analysis links 98 genes to neurodevelopmental conditions

Genetic sequences from nearly 53,000 people with autism, developmental delay or intellectual disability reveal strong ties to 98 genes.

By Peter Hess
10 December 2020 | 4 min read

Decade of data dents idea of a ‘female protective effect’

Brothers and sisters of people with autism are both about two to three times more likely than the general population to have an autistic child themselves.

By Peter Hess
12 June 2020 | 4 min read
colorful micrograph of cells dividing

Whole-genome study lifts veil on inheritance patterns in autism

An analysis of whole-genome sequences from nearly 500 families has implicated 16 new genes in autism.

By Lauren Schenkman
19 September 2019 | 4 min read

Genetics do-over; iffy influences; high-tech education and more

A re-analysis of data yields an increased estimate for the genetic contribution to autism, how the environment might contribute to autism is hard to pin down, and students on the spectrum describe the benefits of using technology at school.

By Emily Willingham
29 September 2017 | 5 min read

Mitochondrial risk; anxiety amelioration; fever factor and more

Some variants in mitochondrial DNA are more common than others in autism, cognitive therapy reduces anxiety for people on the spectrum, and maternal fever in the third trimester is tied to autism risk.

By Emily Willingham
25 August 2017 | 5 min read

Explore more from The Transmitter

Illustrated collage of a monkey profile, a gloved hand holding a vaccine syringe touching an outline of the United States with two primates sitting near it, a strand of DNA, and flags of the United States and China in the background.

U.S. national primate research centers face an uncertain future

The facilities were meant to last 100 years. Four decades shy of that mark, amid flatlined funds and mounting political pressure, their directors are trying to find a path forward.

By Calli McMurray
9 October 2026 | 12 min read
Reflections of primates in lab equipment (bottom left: Rhesus macaque, top left: Pig-tailed macaque, bottom right: Crab-eating macaque. top right: Marmoset

What if nonhuman primate research goes away?

As the U.S. government takes steps to stop using nonhuman primates in research, The Transmitter investigates what that shift could mean for neuroscience.

By The Transmitter
9 October 2026 | 2 min read
Illustration of primate hands interacting with objects of cognitive tests.

The neuroscience questions that need nonhuman primates

The Transmitter asked 17 neuroscientists what questions might remain unanswered if support for nonhuman primate research continues to decline.

By Alissa de Chassey
9 October 2026 | 10 min read