Hypothalamus

Recent articles

Research image of astrocytes in a mouse brain.

Astrocytes orchestrate oxytocin’s social effects in mice

The cells amplify oxytocin—and may be responsible for sex differences in social behavior, two preprints find.

By Holly Barker
4 March 2026 | 5 min read
Mouse on top of drinking water spout in crowded cage.

Cracking the neural code for emotional states

Rather than act as a simple switchboard for innate behaviors, the hypothalamus encodes an animal's internal state, which influences behavior.

By Natalia Mesa
8 January 2026 | 8 min read
Abstract flowing shapes.

Perimenopause: An important—and understudied—transition for the brain

Many well-known perimenopause symptoms arise in the brain, but we still know little about the specific mechanisms at play. More research—in both animals and humans—is essential.

By Marija Kundakovic
12 November 2025 | 6 min read
Research image of grids of mouse and human brain scans.

Too much or too little brain synchrony may underlie autism subtypes

Functional connectivity differences in autism mouse models point to two subtypes that correspond to patterns seen in some people with the condition.

By Calli McMurray
17 April 2025 | 6 min read
Two mice sleeping.

Soft touch quells loneliness in mice

Touch modulates one of two dueling types of hypothalamic neurons that, thermostat-like, balance an animal’s drive for social interaction.

By Angie Voyles Askham
26 February 2025 | 6 min read
Research image of gene expression in cells in the third ventricle of the hypothalamus of young and aged mice.

Age-related brain changes in mice strike hypothalamus ‘hot spot’

Neuronal and non-neuronal cells throughout the brain also express genes—particularly those related to neuronal structure and immune function—differently in aged mice, according to a new atlas.

By Angie Voyles Askham
8 January 2025 | 5 min read
Illustration of a mouse melting in front of a fan.

To beat the heat, hypothalamus neurons in mice ramp up their firing

The uptick may help the rodents acclimate to temperature hikes and keep their cool.

By Calli McMurray
11 December 2024 | 7 min read
Research image of brain circuits.

Novel neurons upend ‘yin-yang’ model of hunger, satiety in brain

The new type of leptin-sensitive cells curb hunger quickly—adding to an increasingly complex picture of brain circuits that control feeding behaviors.

By Giorgia Guglielmi
9 December 2024 | 5 min read
A squirrel sleeps on the ground with its toe in its mouth.

Rousing a ‘new era’ of hibernation research

Novel applications of neuroscience tools have enabled researchers to uncover the neural controls of an extreme biological trait.

By Shaena Montanari
8 November 2024 | 9 min read
Illustration of a mouse with cheese on its left and a drop of water on its right.

Should I stay (and eat) or should I go? How the brain balances hunger with competing drives

Understanding the interplay among rival signals, such as pain, thirst and fear, could provide insights into anxiety and other neuropsychiatric conditions.

By Giorgia Guglielmi
11 October 2024 | 8 min read

Explore more from The Transmitter

Illustration of rolling dice.

Grant review needs reform. How about we add an element of chance?

A process that uses a lottery system saves time, reduces strategic resubmission and accepts that, above a quality threshold, luck has always played a part in science funding.

By Adrien Peyrache
25 September 2026 | 6 min read
Research diagram of gene expression.

Fly neurons carry molecular signatures of their origins

The pattern of transcription factors a Drosophila neuron expresses offers clues to its lineage and birth order—and ultimately how neural circuits emerge.

By Alissa de Chassey
25 September 2026 | 5 min read
Cortical organoids from the anterior (green) or posterior (red) cortex.

Polarized cortical organoids mimic the brain’s regional organization

The organoids show region-specific gene-expression changes that match those observed during fetal development.

By Holly Barker
24 September 2026 | 4 min read