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Spectrum is the go-to destination for the latest news and analysis about autism research and a springboard for scientists and clinicians to forge collaborations that deepen our understanding of autism.

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Everyone who has studied sex differences in rodents is going to drop their jaws. — BERNARD MULVEY, POSTDOCTORAL FELLOW, LIEBER INSTITUTE FOR BRAIN DEVELOPMENT

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“Weaponizing uncertainty in science and in public health puts people in harm’s way”
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Spectrum

The perils of parachute research

Scientists who study autism in lower-income countries are working to end practices that exploit or ignore collaborators and communities on the ground.

By Linda Nordling
6 June 2024 | 11 min read
Research video of a zebrafish larva (zoomed in on the gut) being given glucose.
Spectrum

On the periphery: Thinking ‘outside the brain’ offers new ideas about autism

Neuronal alterations outside the brain may help to explain a host of the condition’s characteristic traits, including sensory changes, gut problems and motor differences.

By Sarah DeWeerdt
13 April 2023 | 20 min read
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Research image of human cortical organoids.

Parsing phenotypes in people with shared autism-linked variants; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 13 October.

By Jill Adams
14 October 2025 | 2 min read
Research image of SCN2A neurons.

Boosting SCN2A expression reduces seizures in mice

A modified form of CRISPR amps up expression of the gene—a strategy that could apply to other gene variations linked to autism.

By Charles Q. Choi
9 October 2025 | 5 min read
Research image of neurons with variants of the KCNQ2 gene (bottom row) developing more synaptic protein groups (pink and blue) than control neurons (top row).

ADSI, leucovorin, autism registry; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 6 October.

By Jill Adams
7 October 2025 | 2 min read
Composite of Autism Data Science Initiative researcher headshots.

Meet the Autism Data Science Initiative grantees

The awarded projects plan to study gene-and-environment interactions in people, stem cells and organoids, as well as predictors of positive life outcomes in autistic youth and adults.

By Calli McMurray
3 October 2025 | 2 min read
Stack of papers.

Exclusive: The 23 studies the FDA based its expanded leucovorin label on

The studies include 46 people, mostly toddlers, who have cerebral folate deficiency due to variants in a folate transporter.

By Claudia López Lloreda
2 October 2025 | 6 min read

Explore more from The Transmitter

Remembering GABA pioneer Edward Kravitz

The biochemist, who died last month at age 92, was part of the first neurobiology department in the world and showed that gamma-aminobutyric acid is inhibitory.

By Claudia López Lloreda
24 October 2025 | 9 min listen
Mouse sensory neurons express the ion channel TPRV1 .

Neurons tune electron transport chain to survive onslaught of noxious stimuli

Nociceptors tamp down the production of reactive oxygen species in response to heat, chemical irritants or toxins.

By Viviane Callier
22 October 2025 | 5 min listen

Vicente Raja brings ecological psychology concepts to neuroscience

He suggests neuroscientists should pay more attention to the principles of Gibsonian ecological psychology, such as affordances, ecological information and resonance, to better explain perception and action.

By Paul Middlebrooks
22 October 2025 | 99 min listen

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