Psychedelics

Recent articles

A mouse stands on a gloved hand.

Psychedelics research in rodents has a behavior problem

Simple behavioral assays—originally validated as drug-screening tools—fall short in studies that aim to unpack the psychedelic mechanism of action, so some behavioral neuroscientists are developing more nuanced tasks.

By Calli McMurray
19 December 2025 | 8 min read

Psilocybin rewires specific mouse cortical networks in lasting ways

Neuronal activity induced by the psychedelic drug strengthens inputs from sensory brain areas and weakens cortico-cortical recurrent loops.

By Siddhant Pusdekar
5 December 2025 | 0 min watch
A man with glasses reads from a paper with a graph-like pattern of peaks and valleys on it.

The buzziest neuroscience papers of 2023, 2024

The field took note of work on brain-computer interfaces for speech, the mechanism of psychedelics, a broader definition of hippocampal representations, and more.

By Calli McMurray, Francisco J. Rivera Rosario
15 November 2025 | 18 min read
Research image of altered neurovascular coupling after exposure to psychedelics.

Psychedelics muddy fMRI results: Q&A with Adam Bauer and Jonah Padawer-Curry

The drugs disrupt the link between vascular and neuronal activity, which complicates interpretations of fMRI data. Adopting a more holistic view of what constitutes brain activity may help, the researchers say.

By Calli McMurray
29 October 2025 | 7 min read
Illustration of a brain surrounded by a stylized silhouette of a human head with psychedelic colors and textures.

Why we need basic science to better understand the neurobiology of psychedelics

Despite the many psychedelics clinical trials underway, there is still much we don’t know about how these drugs work. Preclinical studies represent our best viable avenue to answer these lingering questions.

By Devin Effinger, Melissa Herman
1 October 2025 | 6 min read
Crumpled pieces of paper form an X.

Psychedelics meta-analysis retracted after authors request ‘significant changes’

While working on a similar analysis last year, an independent researcher spotted inconsistencies in the now-retracted paper.

By Marta Hill
11 June 2025 | 2 min read

Explore more from The Transmitter

Brain network maps creating using lesion network mapping.

Methodological flaw may upend network mapping tool

The lesion network mapping method, used to identify disease-specific brain networks for clinical stimulation, produces a nearly identical network map for any given condition, according to a new study.

By Angie Voyles Askham
15 January 2026 | 7 min read
Crowd seen from above.

Common and rare variants shape distinct genetic architecture of autism in African Americans

Certain gene variants may have greater weight in determining autism likelihood for some populations, a new study shows.

By Laura Dattaro
15 January 2026 | 5 min read
Research image of stem cells derived from people of African ancestry.

Bringing African ancestry into cellular neuroscience

Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.

By Lauren Schenkman
14 January 2026 | 7 min read

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