Modeling
Recent articles
Long-sought walking circuit found in fruit flies
The neuronal circuit controlling repetitive locomotion patterns in any animal has been a mystery until now.
Long-sought walking circuit found in fruit flies
The neuronal circuit controlling repetitive locomotion patterns in any animal has been a mystery until now.
‘Digital sphinx’ raises questions about connectome models
The sphinx, with a worm’s brain and a fly’s body, illustrates the potential pitfalls of using deep-learning techniques to model biological processes.
‘Digital sphinx’ raises questions about connectome models
The sphinx, with a worm’s brain and a fly’s body, illustrates the potential pitfalls of using deep-learning techniques to model biological processes.
David Sussillo on persistence, luck and the bonds between life and work
In a Q&A about his new book, “Emergence,” Sussillo shares why he wrote it and how challenging circumstances shaped his journey into neuroscience.
David Sussillo on persistence, luck and the bonds between life and work
In a Q&A about his new book, “Emergence,” Sussillo shares why he wrote it and how challenging circumstances shaped his journey into neuroscience.
How to collaborate with AI
To make the best use of LLMs in research, turn your scientific question into a set of concrete, checkable proposals, wire up an automatic scoring loop, and let the AI iterate.
How to collaborate with AI
To make the best use of LLMs in research, turn your scientific question into a set of concrete, checkable proposals, wire up an automatic scoring loop, and let the AI iterate.
Bringing African ancestry into cellular neuroscience
Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.
Bringing African ancestry into cellular neuroscience
Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.
The 1,000 neuron challenge
A competition to design small, efficient neural models might provide new insight into real brains—and perhaps unite disparate modeling efforts.
The 1,000 neuron challenge
A competition to design small, efficient neural models might provide new insight into real brains—and perhaps unite disparate modeling efforts.
The Transmitter’s favorite essays of 2025
Throughout a tumultuous year in science, researchers opined on policy changes and funding uncertainty, as well as scientific trends and the impact of artificial-intelligence tools on the field.
The Transmitter’s favorite essays of 2025
Throughout a tumultuous year in science, researchers opined on policy changes and funding uncertainty, as well as scientific trends and the impact of artificial-intelligence tools on the field.
What is the future of organoid and assembloid regulation?
Four experts weigh in on how to establish ethical guardrails for research on the 3D neuron clusters as these models become ever more complex.
What is the future of organoid and assembloid regulation?
Four experts weigh in on how to establish ethical guardrails for research on the 3D neuron clusters as these models become ever more complex.
Tatiana Engel explains how to connect high-dimensional neural circuitry with low-dimensional cognitive functions
Neuroscientists have long sought to understand the relationship between structure and function in the vast connectivity and activity patterns in the brain. Engel discusses her modeling approach to discovering the hidden patterns that connect the two.
Tatiana Engel explains how to connect high-dimensional neural circuitry with low-dimensional cognitive functions
Neuroscientists have long sought to understand the relationship between structure and function in the vast connectivity and activity patterns in the brain. Engel discusses her modeling approach to discovering the hidden patterns that connect the two.
Whole-brain, bottom-up neuroscience: The time for it is now
Applying new tools to entire brains, starting with C. elegans, offers the opportunity to uncover how molecules work together to generate neural physiology and how neurons work together to generate behavior.
Whole-brain, bottom-up neuroscience: The time for it is now
Applying new tools to entire brains, starting with C. elegans, offers the opportunity to uncover how molecules work together to generate neural physiology and how neurons work together to generate behavior.
Explore more from The Transmitter
Still no proof for facilitated spelling methods
A systematic review into whether the “rapid prompting method” or “spelling to communicate” can help autistic people express themselves comes up empty yet again.
Still no proof for facilitated spelling methods
A systematic review into whether the “rapid prompting method” or “spelling to communicate” can help autistic people express themselves comes up empty yet again.
Oregon primate center scientists fight proposed sanctuary transition
A group of employees has launched a series of campaigns to advocate for their work and argue against the center’s potential transition to an animal sanctuary.
Oregon primate center scientists fight proposed sanctuary transition
A group of employees has launched a series of campaigns to advocate for their work and argue against the center’s potential transition to an animal sanctuary.
When autistic kids grow up
An autistic researcher’s paper called attention to a huge disparity in autism funding research between children and adults. It nearly derailed her life.
When autistic kids grow up
An autistic researcher’s paper called attention to a huge disparity in autism funding research between children and adults. It nearly derailed her life.