Modeling
Recent articles
How energy determines where proteins are produced in neurons
Tatjana Tchumatchenko explains how mathematical modeling elucidates whether ion-channel proteins are produced locally in the soma or in the dendrites.
How energy determines where proteins are produced in neurons
Tatjana Tchumatchenko explains how mathematical modeling elucidates whether ion-channel proteins are produced locally in the soma or in the dendrites.
Study questions DSM-5’s combining of autism traits
Sensory traits and restricted and repetitive behaviors are best understood as distinct but related characteristics, the new work suggests.
Study questions DSM-5’s combining of autism traits
Sensory traits and restricted and repetitive behaviors are best understood as distinct but related characteristics, the new work suggests.
Long-sought walking circuit found in fruit flies
The neuronal circuit controlling repetitive locomotion patterns in any animal has been a mystery until now.
Long-sought walking circuit found in fruit flies
The neuronal circuit controlling repetitive locomotion patterns in any animal has been a mystery until now.
‘Digital sphinx’ raises questions about connectome models
The sphinx, with a worm’s brain and a fly’s body, illustrates the potential pitfalls of using deep-learning techniques to model biological processes.
‘Digital sphinx’ raises questions about connectome models
The sphinx, with a worm’s brain and a fly’s body, illustrates the potential pitfalls of using deep-learning techniques to model biological processes.
David Sussillo on persistence, luck and the bonds between life and work
In a Q&A about his new book, “Emergence,” Sussillo shares why he wrote it and how challenging circumstances shaped his journey into neuroscience.
David Sussillo on persistence, luck and the bonds between life and work
In a Q&A about his new book, “Emergence,” Sussillo shares why he wrote it and how challenging circumstances shaped his journey into neuroscience.
How to collaborate with AI
To make the best use of LLMs in research, turn your scientific question into a set of concrete, checkable proposals, wire up an automatic scoring loop, and let the AI iterate.
How to collaborate with AI
To make the best use of LLMs in research, turn your scientific question into a set of concrete, checkable proposals, wire up an automatic scoring loop, and let the AI iterate.
Bringing African ancestry into cellular neuroscience
Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.
Bringing African ancestry into cellular neuroscience
Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.
The 1,000 neuron challenge
A competition to design small, efficient neural models might provide new insight into real brains—and perhaps unite disparate modeling efforts.
The 1,000 neuron challenge
A competition to design small, efficient neural models might provide new insight into real brains—and perhaps unite disparate modeling efforts.
The Transmitter’s favorite essays of 2025
Throughout a tumultuous year in science, researchers opined on policy changes and funding uncertainty, as well as scientific trends and the impact of artificial-intelligence tools on the field.
The Transmitter’s favorite essays of 2025
Throughout a tumultuous year in science, researchers opined on policy changes and funding uncertainty, as well as scientific trends and the impact of artificial-intelligence tools on the field.
Not playing around: Why neuroscience needs toy models
Amid the rise of billion-parameter models, I argue that toy models, with just a few neurons, remain essential—and may be all neuroscience needs.
Not playing around: Why neuroscience needs toy models
Amid the rise of billion-parameter models, I argue that toy models, with just a few neurons, remain essential—and may be all neuroscience needs.
Explore more from The Transmitter
Amid funding uncertainty, neuroscientists report a mix of cynicism, persistence
Two years into one of the most tumultuous tenures in U.S. federal funding, researchers outline how they are coping with ongoing changes and reflect on the impact these changes are having on the system more broadly.
Amid funding uncertainty, neuroscientists report a mix of cynicism, persistence
Two years into one of the most tumultuous tenures in U.S. federal funding, researchers outline how they are coping with ongoing changes and reflect on the impact these changes are having on the system more broadly.
Reimagining Mexico’s brain bank
Since Alzheimer’s disease researcher José Luna-Muñoz assumed leadership of the facility—Latin America’s oldest—in 2011, he has been acquiring additional tissue types and is working to expand donor recruitment to rural areas.
Reimagining Mexico’s brain bank
Since Alzheimer’s disease researcher José Luna-Muñoz assumed leadership of the facility—Latin America’s oldest—in 2011, he has been acquiring additional tissue types and is working to expand donor recruitment to rural areas.
Revealing how crabs make their escape
Houdini-like Neohelice granulata offers a rare opportunity to record intracellularly from awake, behaving animals.
Revealing how crabs make their escape
Houdini-like Neohelice granulata offers a rare opportunity to record intracellularly from awake, behaving animals.