Modeling
Recent articles
How brains prevent ‘catastrophic forgetting’
Dendrite-specific inhibition lets overlapping neuronal assemblies form across brain areas without erasing existing memories, a new modeling study suggests.
How brains prevent ‘catastrophic forgetting’
Dendrite-specific inhibition lets overlapping neuronal assemblies form across brain areas without erasing existing memories, a new modeling study suggests.
Neuromechanical models deepen our understanding of animal motor control
Thanks to recent progress in physics-based simulators and robotics, it has never been easier for neuroscientists to use neuromechanical modeling to test hypotheses about animal movement.
Neuromechanical models deepen our understanding of animal motor control
Thanks to recent progress in physics-based simulators and robotics, it has never been easier for neuroscientists to use neuromechanical modeling to test hypotheses about animal movement.
How energy determines where proteins are produced in neurons
Tatjana Tchumatchenko explains how mathematical modeling elucidates whether ion-channel proteins are produced locally in the soma or in the dendrites.
How energy determines where proteins are produced in neurons
Tatjana Tchumatchenko explains how mathematical modeling elucidates whether ion-channel proteins are produced locally in the soma or in the dendrites.
Study questions DSM-5’s combining of autism traits
Sensory traits and restricted and repetitive behaviors are best understood as distinct but related characteristics, the new work suggests.
Study questions DSM-5’s combining of autism traits
Sensory traits and restricted and repetitive behaviors are best understood as distinct but related characteristics, the new work suggests.
Long-sought walking circuit found in fruit flies
The neuronal circuit controlling repetitive locomotion patterns in any animal has been a mystery until now.
Long-sought walking circuit found in fruit flies
The neuronal circuit controlling repetitive locomotion patterns in any animal has been a mystery until now.
‘Digital sphinx’ raises questions about connectome models
The sphinx, with a worm’s brain and a fly’s body, illustrates the potential pitfalls of using deep-learning techniques to model biological processes.
‘Digital sphinx’ raises questions about connectome models
The sphinx, with a worm’s brain and a fly’s body, illustrates the potential pitfalls of using deep-learning techniques to model biological processes.
David Sussillo on persistence, luck and the bonds between life and work
In a Q&A about his new book, “Emergence,” Sussillo shares why he wrote it and how challenging circumstances shaped his journey into neuroscience.
David Sussillo on persistence, luck and the bonds between life and work
In a Q&A about his new book, “Emergence,” Sussillo shares why he wrote it and how challenging circumstances shaped his journey into neuroscience.
How to collaborate with AI
To make the best use of LLMs in research, turn your scientific question into a set of concrete, checkable proposals, wire up an automatic scoring loop, and let the AI iterate.
How to collaborate with AI
To make the best use of LLMs in research, turn your scientific question into a set of concrete, checkable proposals, wire up an automatic scoring loop, and let the AI iterate.
Bringing African ancestry into cellular neuroscience
Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.
Bringing African ancestry into cellular neuroscience
Two independent teams in Africa are developing stem cell lines and organoids from local populations to explore neurodevelopmental and neurodegenerative conditions.
The 1,000 neuron challenge
A competition to design small, efficient neural models might provide new insight into real brains—and perhaps unite disparate modeling efforts.
The 1,000 neuron challenge
A competition to design small, efficient neural models might provide new insight into real brains—and perhaps unite disparate modeling efforts.
Explore more from The Transmitter
Remembering Gerry Fischbach, ‘orchestra conductor’ who brought scientists together
Fischbach, who died 25 October, elucidated the dynamic changes in neuromuscular junctions. Beyond the lab, he shaped careers, academic departments and scientific societies.
Remembering Gerry Fischbach, ‘orchestra conductor’ who brought scientists together
Fischbach, who died 25 October, elucidated the dynamic changes in neuromuscular junctions. Beyond the lab, he shaped careers, academic departments and scientific societies.
WILD platform levels up ability to record brain activity, behavior in nature
The customizable rig combines multimodal recording, onboard processing and neuronal manipulation to power more complex experiments.
WILD platform levels up ability to record brain activity, behavior in nature
The customizable rig combines multimodal recording, onboard processing and neuronal manipulation to power more complex experiments.
The relationship between structure and function in cortical networks
Michael Reimann explains how the shape of neurons puts strong constraints on how they are wired in a network, and how this affects their structure-function relationships.
The relationship between structure and function in cortical networks
Michael Reimann explains how the shape of neurons puts strong constraints on how they are wired in a network, and how this affects their structure-function relationships.