Electrophysiology

Recent articles

Research image of cursor movement from high gamma activity.

Recording warning: Common brain signal may be misunderstood

High gamma activity in electrophysiologic recordings reflects widespread neural activity, not merely local firing, as previously thought.

By Claudia López Lloreda
30 June 2026 | 5 min read
Connexiohuman Connexin 26 dodecamer at 90mmHg PCO2, pH7.4

Designer synapses edit brain circuits in living animals

The approach could help elucidate relationships between circuit structure and function, as well as the role of natural electrical synapses.

By Simon Makin
23 June 2026 | 5 min read

Cortical area remixes macaques’ knowledge blocks to solve new problems

When monkeys draw complex shapes, their neural activity reflects patterns of activation elicited by drawing simpler, component shapes.

By Lauren Schenkman
19 June 2026 | 0 min watch

Snoozing dragons stir up ancient evidence of sleep’s dual nature

Deep-sleep cycling between brain waves of higher and lower amplitude dates far back on the evolutionary tree, according to a new comparative study of mammals and reptiles.

By Lauren Schenkman
29 December 2025 | 0 min watch

Facial movements telegraph cognition in mice

If you give a mouse a decision, its thought process may show on its face.

By Lauren Schneider
30 September 2025 | 0 min watch
Illustration of a multiple mouse brains and brain slices converging onto one animal.

Reproducibility is a team sport: Lessons from a large-scale collaboration

Building reproducible systems across labs is possible, even in large-scale neuroscience projects. You just need rigor, collaboration and the willingness to look your own practices dead in the eye.

By Anne Churchland
29 September 2025 | 7 min read
Research image of mouse brain activity during a decision-making task.

Everything everywhere all at once: Decision-making signals engage entire brain

The findings, gleaned from the most comprehensive map yet of brain activity during decision-making in mice, show that the process is even more distributed than previously thought.

By Claudia López Lloreda
3 September 2025 | 5 min read
A James Hudspeth.

Remembering A. James Hudspeth, hair cell explorer

Hudspeth, who died 16 August at age 79, devoted his 50-year career to untangling how the ear converts sound into electrical signals.

By Calli McMurray
21 August 2025 | 7 min read
Research image of red and blue light emitted from the Neuropixels Opto probe.

‘Perturb and record’ optogenetics probe aims precision spotlight at brain structures

The tool provides a new way to characterize cells and study neuronal circuits.

By Claudia López Lloreda
29 April 2025 | 4 min read

Explore more from The Transmitter

Susumu Tonegawa.

In memoriam: Susumu Tonegawa, ‘intellectual giant’

He won the Nobel Prize for his work on immunology and then went on to define the field of learning and memory.

By Claudia López Lloreda
17 July 2026 | 6 min read
Research image of mouse and human Purkinje cells.

Purkinje cells evolved to have increasingly complex architecture

An increasing proportion of the cerebellar neurons acquired multiple primary dendrites in humans and other apes, according to a comparison of 11 primate species.

By Siddhant Pusdekar
16 July 2026 | 5 min read
Research image of mouse brain.

Making waves: Sleep-like brain activity in awake mice lowers sleep need, boosts memory

Alternating on/off firing patterns don’t just characterize deep, slow-wave sleep, they drive some of its restorative benefits, new findings suggest.

By Alissa de Chassey
16 July 2026 | 4 min read