Systems neuroscience

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Headshots of Karl Deisseroth, Peter Hegemann and Georg Nagel.

How Nobel Prize-winning optogenetics has revolutionized neuroscience

The technique has enabled neuroscientists to target brain circuits and cells with unprecedented specificity, transforming the study of memory, interoception, brain disorders and reward, among other domains.

Illustration of two cats jumping to opposite buildings in a city.

Is confidence a second thought—or part of the first one?

In some settings, neural circuits may calculate confidence in a decision simultaneously with the choice itself. That changes the types of questions researchers should ask.

By Ariel Zylberberg
5 October 2026 | 6 min read
Research diagram of task-aligned activity rasters.

Cerebellar neurons reorient brain activity to differentiate similar behaviors

The findings provide a new perspective on how granule cells help to generalize learning across tasks.

By Holly Barker
29 September 2026 | 4 min read

Neuromechanical models deepen our understanding of animal motor control

Thanks to recent progress in physics-based simulators and robotics, it has never been easier for neuroscientists to use neuromechanical modeling to test hypotheses about animal movement.

By Auke Ijspeert
9 September 2026 | 0 min watch
Illustration of three steps to build an origami polyhedron.

Dimensionality—neuroscience’s red herring?

Placing too much emphasis on a specific interpretation of dimensionality, or treating it as an end-all quantification of some aspect of neural computation, may hinder progress in understanding the brain.

By Matthew Perich
7 September 2026 | 8 min read

Explore more from The Transmitter

Fiona Sanderson photo illustration.

Creating community through grant support

Fiona Sanderson, a senior program manager at the Brain Canada Foundation, shares how she got into grant administration and how she helps connect researchers with funding and one another.

By Katie Moisse
14 October 2026 | 7 min read
Illustration of the brain processing different shapes.

This paper changed my life: A first glimpse into the ‘middle’ of brain processing

Work by Jeffrey Moran and Robert Desimone showed that monkeys could focus their attention on different stimuli in their visual field without shifting their gaze. Their work marked a key milestone in the emergence of cognitive neuroscience.

By Earl K. Miller
14 October 2026 | 3 min read
Research image of resting-state functional MRI.

Acetaminophen effects on developing brain organoids; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 12 October.

By Jill Adams
13 October 2026 | 1 min read