Hippocampus
The value of math and spatial learning with Loren Frank
The Howard Hughes Medical Institute investigator discusses what drew him to study the brain and his current work at the University of California, San Francisco.
The value of math and spatial learning with Loren Frank
Microglial overreaction to atypical neurons may drive autism
In mice and organoids lacking a neuronal protein, microglia prune synapses to excess.
Microglial overreaction to atypical neurons may drive autism
How to teach this paper: ‘Creating a false memory in the hippocampus,’ by Ramirez and Liu et al. (2013)
We’ve known how to implant memories in mouse minds for a decade. Can we implant these ideas in our students?
Being uncomfortable and PKMzeta with André Fenton
The director of the Center for Neural Science shares a ghost story and talks about his collaboration with Todd Sacktor.
Being uncomfortable and PKMzeta with André Fenton
Temperament is innate but hackable, animal studies suggest
Emotional reactivity and vulnerability to stress are largely inherited in rodents — but can be modified in early life by targeting inflammation-related cells or even just adjusting an animal’s environment.
Temperament is innate but hackable, animal studies suggest
Immune-activation model mice escape infantile amnesia, retain early memories
Male pups born to mothers treated with immune-stimulating molecules show autism-like behaviors and, unlike wildtype animals, do not lose memories formed during early life.
Immune-activation model mice escape infantile amnesia, retain early memories
‘Into the wild’: Moving studies of memory and learning out of the lab
People with electrodes embedded deep in their brain are collaborating with a growing posse of plucky researchers to uncover the mysteries of real-world recall.
‘Into the wild’: Moving studies of memory and learning out of the lab
New specs immerse mice in virtual worlds
The tool — called “MouseGoggles” — could provide rodents with an improved virtual experience in the lab, at a lower cost than current techniques.
Some social issues in DYRK1A model mice stem from faulty inhibitory circuits
Alterations in inhibitory circuits and difficulties in social recognition characterize mice missing one copy of DYRK1A, a gene linked to autism.
Some social issues in DYRK1A model mice stem from faulty inhibitory circuits
Cannabis compound rebalances signaling to quell seizures in mice
Cannabidiol (CBD) blocks the action of a molecule that drives an overexcitability feedback loop in a rodent model of epilepsy.
Cannabis compound rebalances signaling to quell seizures in mice
Explore more from The Transmitter
Rat neurons thrive in a mouse brain world, testing ‘nature versus nurture’
Neurons from the two rodents can wire up together to form functional circuits—all while maintaining some species-specific properties, two new studies show.
Rat neurons thrive in a mouse brain world, testing ‘nature versus nurture’
Neurons from the two rodents can wire up together to form functional circuits—all while maintaining some species-specific properties, two new studies show.
It’s past time to stop using the Reading the Mind in the Eyes Test
The widely used measure of “theory of mind” needs to be re-examined, along with the long-standing claim that autism is linked to a lack of this ability.
It’s past time to stop using the Reading the Mind in the Eyes Test
The widely used measure of “theory of mind” needs to be re-examined, along with the long-standing claim that autism is linked to a lack of this ability.
Robots boost data consistency in rodent studies reliant on mechanical, optogenetic stimulation
Two new devices take experimenter variation out of the equation, the lead investigators say.
Robots boost data consistency in rodent studies reliant on mechanical, optogenetic stimulation
Two new devices take experimenter variation out of the equation, the lead investigators say.