Hyperactivity
Mental health issues emerge with shifts in autism traits across childhood
Anxiety and other challenges autistic children experience may stem from an increase in social-communication issues and a decrease in repetitive behaviors from ages 6 to 11.
Mental health issues emerge with shifts in autism traits across childhood
Serotonin powers pruning of developing brain circuits in mice
Mice with microglia missing receptors for the neurotransmitter serotonin since birth have too many synapses and show social difficulties in adulthood.
Serotonin powers pruning of developing brain circuits in mice
Autism-related genes converge on microglia and dopamine in zebrafish
The findings add to the growing evidence that genes with disparate functions can play similar roles in brain development.
Autism-related genes converge on microglia and dopamine in zebrafish
Autism-linked MYT1L mutations prompt ‘identity crisis’ in budding brain cells
Both human and mouse progenitor cells with the alterations struggle to become neurons and instead express genes that are typically active only in muscle or the heart.
Autism-linked MYT1L mutations prompt ‘identity crisis’ in budding brain cells
Mouse model reveals root of breathing issues in rare form of autism
Dysfunctional circuits and a rogue sodium channel in the brainstem may explain the disordered breathing pattern seen in children with Pitt-Hopkins syndrome, a form of autism.
Mouse model reveals root of breathing issues in rare form of autism
Precocious neurons may stunt brain growth in rare form of autism
The first animal model of MYT1L syndrome suggests that fast-maturing neurons lead to the unusually small brains, social deficits and other traits seen in people with the condition.
Precocious neurons may stunt brain growth in rare form of autism
Stimulant restores cell signaling, eases behavior issues in animals missing autism gene
Worms and zebrafish missing both copies of the gene CHD7 have disrupted cellular signaling, a dearth of inhibitory neurons and behavior changes — all of which are reversed by the stimulant drug ephedrine.
Stimulant restores cell signaling, eases behavior issues in animals missing autism gene
Virus-based method manipulates inhibitory neurons in brains
A new viral tool can selectively control different types of neurons that dampen brain activity in rodents, monkeys and people.
Virus-based method manipulates inhibitory neurons in brains
Long-term study tracks persistence of self-harm in autistic people
Autistic people who are hyperactive or have difficulty controlling their own impulses are the most likely to show ongoing self-injury.
Long-term study tracks persistence of self-harm in autistic people
Traits of autism, attention deficit linked to small brainstem
The severity of autism tracks closely with that of attention deficit hyperactivity disorder.
Traits of autism, attention deficit linked to small brainstem
Explore more from The Transmitter
It’s past time to stop using the Reading the Mind in the Eyes Test
The widely used measure of “theory of mind” needs to be re-examined, along with the long-standing claim that autism is linked to a lack of this ability.
It’s past time to stop using the Reading the Mind in the Eyes Test
The widely used measure of “theory of mind” needs to be re-examined, along with the long-standing claim that autism is linked to a lack of this ability.
Robots boost data consistency in rodent studies reliant on mechanical, optogenetic stimulation
Two new devices take experimenter variation out of the equation, the lead investigators say.
Robots boost data consistency in rodent studies reliant on mechanical, optogenetic stimulation
Two new devices take experimenter variation out of the equation, the lead investigators say.
Spina bifida; MDMA effects in a mouse model of autism; maternal autoantibodies
Here is a roundup of autism-related news and research spotted around the web for the week of 13 May.
Spina bifida; MDMA effects in a mouse model of autism; maternal autoantibodies
Here is a roundup of autism-related news and research spotted around the web for the week of 13 May.