Schizophrenia

Recent articles

Novel assembloid illuminates serotonin changes linked to 22q11.2 deletion

The combination of a serotonin-producing organoid with an organoid based on the developing cerebral cortex offers a new way to investigate neuromodulation.

By Sarah DeWeerdt
30 April 2026 | 0 min watch
Data visualization from a genome-wide association study.

Revised statistical bar extracts less-common variants from autism genetics studies

Adjusting genetic analyses could help plug autism’s heritability gap, according to a new preprint.

By Holly Barker
12 March 2026 | 4 min read
A network of connected dots of light hovers inside a translucent human head, with figures in lab coats pointing to it from the foreground.

Computational psychiatry needs systems neuroscience

Dissecting different parallel processing streams may help us understand the mechanisms underlying psychiatric symptoms, such as delusions, and unite human and animal research.

By Michael Halassa
13 January 2026 | 7 min read
Hands arrange various shapes over a color background.

Emotion research has a communication conundrum

In 2025, the words we use to describe emotions matter, but their definitions are controversial. Here, I unpack the different positions in this space and the rationales behind them—and I invite 13 experts to chime in.

By Nicole Rust
5 September 2025 | 29 min read
Illustration of a line graph emanating from a beaker.

Null and Noteworthy, relaunched: Probing a schizophrenia biomarker

This edition of Null and Noteworthy—the first for The Transmitter—highlights new findings about the auditory steady-state response in people with schizophrenia that, all within one study, somehow packed in a null result and a failed replication.

By Laura Dattaro
28 February 2025 | 5 min read
Illustration of two silhouettes overlaid by opaque square panels.

Why hasn’t genetics taught us more about schizophrenia?

Large-scale genomics studies have failed to identify specific pathways that go awry in schizophrenia. Alternative approaches focusing on cellular, molecular and systems-level changes may be needed.

By Joshua R. Sanes
18 February 2025 | 8 min read

Assembloids illuminate circuit-level changes linked to autism, neurodevelopment

These complex combinations of organoids afford a closer look at how gene alterations affect certain brain networks.

By Sarah DeWeerdt
19 December 2024 | 0 min watch
Research image of mouse brain slices.

Newfound gene network controls long-range connections between emotional, cognitive brain areas

The finding could help unravel gene regulatory networks and explain how genetic and environmental factors interact in neurodevelopmental conditions.

By Charles Q. Choi
14 November 2024 | 4 min read
A younger looking set of hands holds an older looking set of hands.

New catalog charts familial ties from autism to 90 other conditions

The research tool reveals associations stretching across three generations.

By Charles Q. Choi
17 October 2024 | 4 min read
Stock photograph of a women and her young child at a clinician’s office.

A genetics-first clinic for catching developmental conditions early: Q&A with Jacob Vorstman

A new clinic is assessing children who have a genetic predisposition for autism and other neurodevelopmental conditions—sometimes before traits appear.

By Lauren Schenkman
15 August 2024 | 7 min read

Explore more from The Transmitter

Mother mouse and her offspring.

Maternity induces lasting gene-expression changes in mouse brains

The findings add to a small but growing body of research on neurological changes linked to pregnancy, birth and parenting.

By Amber Dance
12 June 2026 | 5 min read
Map of socioeconomic opportunity in the United States next to visualizations of functional connectivity and structure in sensory and motor cortices.

IQ’s link to brain structure, function in children may be a mirage

A child’s socioeconomic status, screen time and amount of sleep all show stronger associations with measures of brain structure and function, according to an imaging study of nearly 12,000 9- to 10-year-olds.

By Natalia Mesa
11 June 2026 | 5 min read
Photo collage of Tempest McDonald.

When autistic kids grow up, Chapter 2: “You need to go to college”

With just a high school equivalency degree and struggling as a single mother, Tempest McDonald is forced to shift her priorities.

By Brady Huggett
11 June 2026 | 28 min listen