Valproic acid
Recent articles
Brain ‘chimeroids’ reveal person-to-person differences rooted in genetics
These fusions created from multiple donors’ organoids may help scale up comparative brain research.
Brain ‘chimeroids’ reveal person-to-person differences rooted in genetics
These fusions created from multiple donors’ organoids may help scale up comparative brain research.
Chromatin remodeling tied to altered splicing in autism model
Exposing neurons to valproic acid, a well-known environmental risk factor for autism, disrupts their ability to generate different proteins from the same gene.
Chromatin remodeling tied to altered splicing in autism model
Exposing neurons to valproic acid, a well-known environmental risk factor for autism, disrupts their ability to generate different proteins from the same gene.
U.K. health authority investigates epilepsy drug’s link to autism
Prenatal exposure to topiramate increases a child’s autism odds, according to the study that prompted the inquiry, but experts caution that pregnant people with epilepsy have few other options for controlling seizures.
U.K. health authority investigates epilepsy drug’s link to autism
Prenatal exposure to topiramate increases a child’s autism odds, according to the study that prompted the inquiry, but experts caution that pregnant people with epilepsy have few other options for controlling seizures.
Rat model of autism shows unusual brain growth at birth
The brains of rats exposed in utero to the seizure drug valproate show a significant increase in brain size around the time of birth.
Rat model of autism shows unusual brain growth at birth
The brains of rats exposed in utero to the seizure drug valproate show a significant increase in brain size around the time of birth.
How pregnancy may shape a child’s autism
Autism is predominantly genetic in origin, but a growing list of prenatal exposures for mother and baby may sway the odds.
How pregnancy may shape a child’s autism
Autism is predominantly genetic in origin, but a growing list of prenatal exposures for mother and baby may sway the odds.
New restrictions on epilepsy drug may do more harm than good
A partial ban in Europe on the use of a drug called valproate during pregnancy could deny women effective treatment for serious conditions.
New restrictions on epilepsy drug may do more harm than good
A partial ban in Europe on the use of a drug called valproate during pregnancy could deny women effective treatment for serious conditions.
Chick model of epilepsy-drug exposure may mimic signs of autism
Exposing fertilized chicken eggs to valproic acid, an epilepsy drug, yields chicks with apparent social deficits.
Chick model of epilepsy-drug exposure may mimic signs of autism
Exposing fertilized chicken eggs to valproic acid, an epilepsy drug, yields chicks with apparent social deficits.
New journal; organoid ethics; acetaminophen association and more
A journal covering autism in adulthood makes its debut, researchers call for an ethical framework for human organoid studies, and the association between acetaminophen and autism risk comes under scrutiny.
New journal; organoid ethics; acetaminophen association and more
A journal covering autism in adulthood makes its debut, researchers call for an ethical framework for human organoid studies, and the association between acetaminophen and autism risk comes under scrutiny.
Fake autism claim; knocking out anesthesia; haunting milestone and more
Despite social media rumors, a British children’s television show does not cause autism; childhood anesthesia is not tied to autism risk; and an adult on the spectrum reaches a haunting milestone
Fake autism claim; knocking out anesthesia; haunting milestone and more
Despite social media rumors, a British children’s television show does not cause autism; childhood anesthesia is not tied to autism risk; and an adult on the spectrum reaches a haunting milestone
Rodent ratings reveal periods of vulnerability to harmful exposures
Nongenetic rodent models most relevant to autism tend to be those exposed to environmental agents in the womb or shortly after birth.
Rodent ratings reveal periods of vulnerability to harmful exposures
Nongenetic rodent models most relevant to autism tend to be those exposed to environmental agents in the womb or shortly after birth.
Explore more from The Transmitter
International scientific collaboration is more necessary—yet more challenging—than ever
These partnerships accelerate neuroscience by enabling researchers to share resources and expertise, as well as generate more relevant and reproducible results. But new federal funding restrictions in the United States are putting such collaborations in jeopardy.
International scientific collaboration is more necessary—yet more challenging—than ever
These partnerships accelerate neuroscience by enabling researchers to share resources and expertise, as well as generate more relevant and reproducible results. But new federal funding restrictions in the United States are putting such collaborations in jeopardy.
Oxytocin shapes both mouse mom and pup behavior
Distressed pups emit distinct cries for help, which depend on oxytocin neurons in their hypothalamus.
Oxytocin shapes both mouse mom and pup behavior
Distressed pups emit distinct cries for help, which depend on oxytocin neurons in their hypothalamus.
Sensory gatekeeper drives seizures, autism-like behaviors in mouse model
The new work, in mice missing the autism-linked gene CNTNAP2, suggests a mechanism to help explain the overlap between epilepsy and autism.
Sensory gatekeeper drives seizures, autism-like behaviors in mouse model
The new work, in mice missing the autism-linked gene CNTNAP2, suggests a mechanism to help explain the overlap between epilepsy and autism.