Cancer
Going deep: The Transmitter’s top long-form stories in 2023
Our favorite features and book excerpts from the past year delved into the neurobiology of cancer; problems with survey data; free will; mathematical minds; and questions around one startup’s quest to treat brain conditions with cell therapies.
Going deep: The Transmitter’s top long-form stories in 2023
Making cancer nervous
Nerve cells in the brain and throughout the body can turbocharge tumor growth — a finding that not only expands conventional ideas about the nervous system but points to novel therapeutic targets for a range of malignancies.
Mitochondria mediate effects of PTEN mutations
Whole-genome sequencing data — which include information about mitochondrial DNA — offer clues to why mutations in the same gene can lead to autism or cancer.
The cloudy connection between fragile X and cancer
People with the autism-linked syndrome lack a protein implicated in several cancers, but it’s unclear whether — or how — they are protected from malignancies.
The cloudy connection between fragile X and cancer
Two groups of neurons govern autism-like traits in model mice
Together, the neurons are part of the corticostriatal circuit, which has been implicated in autism.
Two groups of neurons govern autism-like traits in model mice
Proteome map identifies more than 90 percent of all human proteins
Researchers expand on the already enormous progress made on the Human Proteome Project
Proteome map identifies more than 90 percent of all human proteins
Scores forecast effects of mutations in autism gene
A new analysis links individual mutations in a gene called PTEN to a person's odds of having autism, cancer or other conditions.
Scores forecast effects of mutations in autism gene
Large mutations may explain diverse outcomes from autism gene
Deletions and duplications of long stretches of DNA may increase the likelihood of autism in people who have a mutation in a gene called PTEN.
Large mutations may explain diverse outcomes from autism gene
Mouse study reveals overlooked target for autism therapies
Blocking one form of an enzyme implicated in autism eases unusual behaviors and seizures in mice missing a top autism gene.
Mouse study reveals overlooked target for autism therapies
CRISPR technique tracks genetic activity in real time
A new method scans gene expression in live cells and could help scientists study autism genes.
CRISPR technique tracks genetic activity in real time
Explore more from The Transmitter
At the credit crossroads: Modern neuroscience needs a cultural shift to adopt new authorship practices
Old heuristics to acknowledge contributors—calling out first and last authors, with everyone else in between—don’t work well for large collaborative and interdisciplinary projects, yet they remain the default.
At the credit crossroads: Modern neuroscience needs a cultural shift to adopt new authorship practices
Old heuristics to acknowledge contributors—calling out first and last authors, with everyone else in between—don’t work well for large collaborative and interdisciplinary projects, yet they remain the default.
Rat neurons thrive in a mouse brain world, testing ‘nature versus nurture’
Neurons from the two rodents can wire up together to form functional circuits—all while maintaining some species-specific properties, two new studies show.
Rat neurons thrive in a mouse brain world, testing ‘nature versus nurture’
Neurons from the two rodents can wire up together to form functional circuits—all while maintaining some species-specific properties, two new studies show.
It’s past time to stop using the Reading the Mind in the Eyes Test
The widely used measure of “theory of mind” needs to be re-examined, along with the long-standing claim that autism is linked to a lack of this ability.
It’s past time to stop using the Reading the Mind in the Eyes Test
The widely used measure of “theory of mind” needs to be re-examined, along with the long-standing claim that autism is linked to a lack of this ability.