Perspectives

Recent articles

Expert opinions on trends and controversies in neuroscience

Illustration of a series of floating pools of water overflowing into each other.

The missing half of the neurodynamical systems theory

Bifurcations—an underexplored concept in neuroscience—can help explain how small differences in neural circuits give rise to entirely novel functions.

By Xiao-Jing Wang
27 October 2025 | 9 min listen
Abstract illustration of a synaptic vesicle.

This paper changed my life: Sandra Jurado marvels at the first-ever 3D model of a synaptic vesicle

In this 2006 Cell paper, Shigeo Takamori and his colleagues showcased the molecular machinery of synaptic vesicles in outstanding detail. Their work taught me that these aren’t just passive containers for neurotransmitters but dynamic, precision-built nanomachines.

By Sandra Jurado
21 October 2025 | 6 min listen
A worm made of circuitry.

Whole-brain, bottom-up neuroscience: The time for it is now

Applying new tools to entire brains, starting with C. elegans, offers the opportunity to uncover how molecules work together to generate neural physiology and how neurons work together to generate behavior.

By Edward Boyden, Konrad Körding
20 October 2025 | 9 min read
Illustration of a series of shapes, with a few resembling human eyes.

The visual system’s lingering mystery: Connecting neural activity and perception

Figuring out how the brain uses information from visual neurons may require new tools. I asked 10 neuroscientists what experimental and conceptual methods they think we’re missing.

By Grace Lindsay
13 October 2025 | 5 min read
A drosophila connectome.

One year of FlyWire: How the resource is redefining Drosophila research

We asked nine neuroscientists how they are using FlyWire data in their labs, how the connectome has transformed the field and what new tools they would like to see in the future.

By Francisco J. Rivera Rosario
7 October 2025 | 19 min listen
Illustration of a brain surrounded by a stylized silhouette of a human head with psychedelic colors and textures.

Why we need basic science to better understand the neurobiology of psychedelics

Despite the many psychedelics clinical trials underway, there is still much we don’t know about how these drugs work. Preclinical studies represent our best viable avenue to answer these lingering questions.

By Devin Effinger, Melissa Herman
1 October 2025 | 7 min listen
Illustration of a multiple mouse brains and brain slices converging onto one animal.

Reproducibility is a team sport: Lessons from a large-scale collaboration

Building reproducible systems across labs is possible, even in large-scale neuroscience projects. You just need rigor, collaboration and the willingness to look your own practices dead in the eye.

By Anne Churchland
29 September 2025 | 8 min listen
Illustration of a hand drawing lines between different points on the outline of a brain.

Beyond Newtonian causation in neuroscience: Embracing complex causality

The traditional mechanistic framework must give way to a richer understanding of how brains actually generate behavior over time.

By Luiz Pessoa
22 September 2025 | 25 min listen
Illustration of human figures holding brightly colored connected dots.

This paper changed my life: Dan Goodman on a paper that reignited the field of spiking neural networks

Friedemann Zenke’s 2019 paper, and its related coding tutorial SpyTorch, made it possible to apply modern machine learning to spiking neural networks. The innovation reinvigorated the field.

By Dan Goodman
17 September 2025 | 5 min listen
Illustration of two researchers attempting to use a microscope that has been twisted into a knot.

International scientific collaboration is more necessary—yet more challenging—than ever

These partnerships accelerate neuroscience by enabling researchers to share resources and expertise, as well as generate more relevant and reproducible results. But new federal funding restrictions in the United States are putting such collaborations in jeopardy.

By Lucina Q. Uddin
15 September 2025 | 6 min listen

Explore more from The Transmitter

Psychedelics muddy fMRI results: Q&A with Adam Bauer and Jonah Padawer-Curry

The drugs disrupt the link between vascular and neuronal activity, which complicates interpretations of fMRI data. Adopting a more holistic view of what constitutes brain activity may help, the researchers say.

By Calli McMurray
29 October 2025 | 7 min read
Headshots of Philip Adeniyi, Samir Ahboucha, Willias Masoch and Daniel Gams Massi.

First Pan-African neuroscience journal gets ready to launch

With lower-than-average article processing fees, and issues dedicated to topics important to the continent, the journal hopes to give African neuroscience research much-needed international visibility.

By Lauren Schenkman
28 October 2025 | 5 min listen
Illustration of an open journal featuring lines of text and small illustrations of eyes and mouths.

New method identifies two-hit genetic variation in autism; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 27 October.

By Jill Adams
28 October 2025 | 2 min read

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