This paper changed my life
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Neuroscientists respond to a set of questions to reflect on a paper that profoundly influenced their career and how they think about their research.
This paper changed my life: Learning the molecular rules of cell identity
A 1987 Cell paper showed that a single transcription factor could turn fibroblasts into muscle cells. The work inspired Ardem Patapoutian to think about the molecular codes that define neuronal subtypes.
This paper changed my life: Learning the molecular rules of cell identity
A 1987 Cell paper showed that a single transcription factor could turn fibroblasts into muscle cells. The work inspired Ardem Patapoutian to think about the molecular codes that define neuronal subtypes.
This paper changed my life: Appreciating John Hopfield’s brilliant neural network
In a 1982 paper, the Nobel laureate created his namesake recurrent neural network—work that taught Maria Geffen to always ground research questions in biology.
This paper changed my life: Appreciating John Hopfield’s brilliant neural network
In a 1982 paper, the Nobel laureate created his namesake recurrent neural network—work that taught Maria Geffen to always ground research questions in biology.
This paper changed my life: Erin Calipari ponders the nuances of rewarding and aversive stimuli
A 1960s study by Kelleher and Morse found that lever pressing in squirrel monkeys depended not on whether they received a reward or shock, but on the rules of the task. This taught Calipari to think deeply about factors that influence how behavior is generated and maintained.
This paper changed my life: Erin Calipari ponders the nuances of rewarding and aversive stimuli
A 1960s study by Kelleher and Morse found that lever pressing in squirrel monkeys depended not on whether they received a reward or shock, but on the rules of the task. This taught Calipari to think deeply about factors that influence how behavior is generated and maintained.
This paper changed my life: Talia Lerner reflects on dopamine neuron diversity and the value of simple experiments
In a 2011 Neuron study, Stephan Lammel and his colleagues showed that dopamine neurons with different projections have different physiological properties. The work inspired Lerner to think about how to challenge widely held assumptions in the field.
This paper changed my life: Talia Lerner reflects on dopamine neuron diversity and the value of simple experiments
In a 2011 Neuron study, Stephan Lammel and his colleagues showed that dopamine neurons with different projections have different physiological properties. The work inspired Lerner to think about how to challenge widely held assumptions in the field.
This paper changed my life: Ishmail Abdus-Saboor on balancing the study of pain and pleasure
A 2013 Nature paper from David Anderson’s lab revealed a group of sensory neurons involved in pleasurable touch and led Abdus-Saboor down a new research path.
This paper changed my life: Ishmail Abdus-Saboor on balancing the study of pain and pleasure
A 2013 Nature paper from David Anderson’s lab revealed a group of sensory neurons involved in pleasurable touch and led Abdus-Saboor down a new research path.
This paper changed my life: John Tuthill reflects on the subjectivity of selfhood
Wittlinger, Wehner and Wolf’s 2006 “stilts and stumps” Science paper revealed how ants pull off extraordinary feats of navigation using a biological odometer, and it inspired Tuthill to consider how other insects sense their own bodies.
This paper changed my life: John Tuthill reflects on the subjectivity of selfhood
Wittlinger, Wehner and Wolf’s 2006 “stilts and stumps” Science paper revealed how ants pull off extraordinary feats of navigation using a biological odometer, and it inspired Tuthill to consider how other insects sense their own bodies.
The best of ‘this paper changed my life’ in 2025
From a study that upended astrocyte research to one that reignited the field of spiking neural networks, experts weighed in on the papers that significantly shaped how they think about and approach neuroscience.
The best of ‘this paper changed my life’ in 2025
From a study that upended astrocyte research to one that reignited the field of spiking neural networks, experts weighed in on the papers that significantly shaped how they think about and approach neuroscience.
This paper changed my life: Nancy Padilla-Coreano on learning the value of population coding
The 2013 Nature paper by Mattia Rigotti and his colleagues revealed how mixed selectivity neurons—cells that are not selectively tuned to a stimulus—play a key role in cognition.
This paper changed my life: Nancy Padilla-Coreano on learning the value of population coding
The 2013 Nature paper by Mattia Rigotti and his colleagues revealed how mixed selectivity neurons—cells that are not selectively tuned to a stimulus—play a key role in cognition.
This paper changed my life: Sandra Jurado marvels at the first-ever 3D model of a synaptic vesicle
In this 2006 Cell paper, Shigeo Takamori and his colleagues showcased the molecular machinery of synaptic vesicles in outstanding detail. Their work taught me that these aren’t just passive containers for neurotransmitters but dynamic, precision-built nanomachines.
This paper changed my life: Sandra Jurado marvels at the first-ever 3D model of a synaptic vesicle
In this 2006 Cell paper, Shigeo Takamori and his colleagues showcased the molecular machinery of synaptic vesicles in outstanding detail. Their work taught me that these aren’t just passive containers for neurotransmitters but dynamic, precision-built nanomachines.
This paper changed my life: Dan Goodman on a paper that reignited the field of spiking neural networks
Friedemann Zenke’s 2019 paper, and its related coding tutorial SpyTorch, made it possible to apply modern machine learning to spiking neural networks. The innovation reinvigorated the field.
This paper changed my life: Dan Goodman on a paper that reignited the field of spiking neural networks
Friedemann Zenke’s 2019 paper, and its related coding tutorial SpyTorch, made it possible to apply modern machine learning to spiking neural networks. The innovation reinvigorated the field.
Explore more from The Transmitter
Cortical area remixes macaques’ knowledge blocks to solve new problems
When monkeys draw complex shapes, their neural activity reflects patterns of activation elicited by drawing simpler, component shapes.
Cortical area remixes macaques’ knowledge blocks to solve new problems
When monkeys draw complex shapes, their neural activity reflects patterns of activation elicited by drawing simpler, component shapes.
Getting grants feels good, but giving them is even better
As director of grants management at the Cure Alzheimer’s Fund, Kaela Singleton bets on bold science and shares in the joy of discovery.
Getting grants feels good, but giving them is even better
As director of grants management at the Cure Alzheimer’s Fund, Kaela Singleton bets on bold science and shares in the joy of discovery.
When autistic kids grow up, Chapter 3: Would there be data?
Tempest McDonald takes a postdoctoral position at Vanderbilt University. Researching her paper accusing the National Institutes of Health of discrimination threatens everything she has built.
When autistic kids grow up, Chapter 3: Would there be data?
Tempest McDonald takes a postdoctoral position at Vanderbilt University. Researching her paper accusing the National Institutes of Health of discrimination threatens everything she has built.