Microglia
Recent articles
Microglia in hypothalamus help kick-start puberty
In a “surprise” role, the cells regulate the neurons that produce gonadotropin-releasing hormone.
Microglia in hypothalamus help kick-start puberty
In a “surprise” role, the cells regulate the neurons that produce gonadotropin-releasing hormone.
Signs of aging vary across brain cells
Senescence presents differently depending on the cell type, toxic trigger and neighboring cells, two new studies find.
Signs of aging vary across brain cells
Senescence presents differently depending on the cell type, toxic trigger and neighboring cells, two new studies find.
Microglia implicated in infantile amnesia
The glial cells could explain the link between maternal immune activation and autism-like behaviors in mice.
Microglia implicated in infantile amnesia
The glial cells could explain the link between maternal immune activation and autism-like behaviors in mice.
Aging neurons outsource garbage disposal, clog microglia
Degradation-resistant proteins pass from neurons to glial cells in a process that may spread protein clumps around the brain, according to a study in mice.
Aging neurons outsource garbage disposal, clog microglia
Degradation-resistant proteins pass from neurons to glial cells in a process that may spread protein clumps around the brain, according to a study in mice.
Astrocytes stabilize circuits in adult mouse brain
The glial cells secrete a protein that suppresses plasticity post-development.
Astrocytes stabilize circuits in adult mouse brain
The glial cells secrete a protein that suppresses plasticity post-development.
How to teach this paper: ‘Neurotoxic reactive astrocytes are induced by activated microglia,’ by Liddelow et al. (2017)
Shane Liddelow and his collaborators identified the factors that transform astrocytes from their helpful to harmful form. Their work is a great choice if you want to teach students about glial cell types, cell culture, gene expression or protein measurement.
How to teach this paper: ‘Neurotoxic reactive astrocytes are induced by activated microglia,’ by Liddelow et al. (2017)
Shane Liddelow and his collaborators identified the factors that transform astrocytes from their helpful to harmful form. Their work is a great choice if you want to teach students about glial cell types, cell culture, gene expression or protein measurement.
This paper changed my life: Shane Liddelow on two papers that upended astrocyte research
A game-changing cell culture method developed in Ben Barres’ lab completely transformed the way we study astrocytes and helped me build a career studying their reactive substates.
This paper changed my life: Shane Liddelow on two papers that upended astrocyte research
A game-changing cell culture method developed in Ben Barres’ lab completely transformed the way we study astrocytes and helped me build a career studying their reactive substates.
Video catches microglia in the act of synaptic pruning
Live cell imaging reveals the clearest picture yet of this elusive process. Whether it’s something these cells do regularly remains up for debate.
Video catches microglia in the act of synaptic pruning
Live cell imaging reveals the clearest picture yet of this elusive process. Whether it’s something these cells do regularly remains up for debate.
Age-related brain changes in mice strike hypothalamus ‘hot spot’
Neuronal and non-neuronal cells throughout the brain also express genes—particularly those related to neuronal structure and immune function—differently in aged mice, according to a new atlas.
Age-related brain changes in mice strike hypothalamus ‘hot spot’
Neuronal and non-neuronal cells throughout the brain also express genes—particularly those related to neuronal structure and immune function—differently in aged mice, according to a new atlas.
Spectrum 2024: Year in review
We round up our most notable autism stories of the past 12 months.
Spectrum 2024: Year in review
We round up our most notable autism stories of the past 12 months.
Explore more from The Transmitter
Designer synapses edit brain circuits in living animals
The approach could help elucidate relationships between circuit structure and function, as well as the role of natural electrical synapses.
Designer synapses edit brain circuits in living animals
The approach could help elucidate relationships between circuit structure and function, as well as the role of natural electrical synapses.
Role of GABA-A receptors in dup15q syndrome, and more
Here is a roundup of autism-related news and research spotted around the web for the week of 22 June.
Role of GABA-A receptors in dup15q syndrome, and more
Here is a roundup of autism-related news and research spotted around the web for the week of 22 June.
Exclusive: Janelia sunsets rodent work, launches transparent fish project
The Howard Hughes Medical Institute’s Janelia Research Campus is banking on whole-brain imaging in the Danionella fish to advance neuroscience, but some scientists forced to close their labs say that even with a three-year runway and transitional support, they feel betrayed by the pivot.
Exclusive: Janelia sunsets rodent work, launches transparent fish project
The Howard Hughes Medical Institute’s Janelia Research Campus is banking on whole-brain imaging in the Danionella fish to advance neuroscience, but some scientists forced to close their labs say that even with a three-year runway and transitional support, they feel betrayed by the pivot.