X chromosome
Recent articles
Exon-skipping approach boosts levels of key Rett syndrome protein
Deleting a small region of the MECP2 gene partially restored function in neurons derived from people with Rett-associated variants.
Exon-skipping approach boosts levels of key Rett syndrome protein
Deleting a small region of the MECP2 gene partially restored function in neurons derived from people with Rett-associated variants.
What birds can teach us about the ‘biological truth’ of sex
Part of our job as educators is to give students a deeper understanding of the true diversity of sex and gender in the natural world.
What birds can teach us about the ‘biological truth’ of sex
Part of our job as educators is to give students a deeper understanding of the true diversity of sex and gender in the natural world.
Revisiting sex and gender in the brain
To conduct scientifically accurate and socially responsible research, it is useful to think of “sex” as a complex, multifactorial and context-dependent variable.
Revisiting sex and gender in the brain
To conduct scientifically accurate and socially responsible research, it is useful to think of “sex” as a complex, multifactorial and context-dependent variable.
X marks the spot in search for autism variants
Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.
X marks the spot in search for autism variants
Genetic variants on the X chromosome, including those in the gene DDX53, contribute to autism’s gender imbalance, two new studies suggest.
Males and females show different patterns of risk for brain-based conditions. Ignoring these differences does us all a disservice.
Although studying sex differences in the brain is complex, technically awkward and socioculturally loaded, it is absolutely essential.
Males and females show different patterns of risk for brain-based conditions. Ignoring these differences does us all a disservice.
Although studying sex differences in the brain is complex, technically awkward and socioculturally loaded, it is absolutely essential.
Accounting for a mosaic of sex differences: Q&A with Nicola Grissom
Breaking the binary view of sex traits can enable researchers to represent the broader complexity of behavior and cognition.
Accounting for a mosaic of sex differences: Q&A with Nicola Grissom
Breaking the binary view of sex traits can enable researchers to represent the broader complexity of behavior and cognition.
Turner syndrome tied to autism
Most people with the X-linked syndrome have autism traits, and about one-quarter meet diagnostic criteria for the condition.
Turner syndrome tied to autism
Most people with the X-linked syndrome have autism traits, and about one-quarter meet diagnostic criteria for the condition.
Silenced X chromosome genes reawaken in new mouse model
The new animal line could accelerate the discovery of gene-activating therapies for the autism-linked condition Rett syndrome.
Silenced X chromosome genes reawaken in new mouse model
The new animal line could accelerate the discovery of gene-activating therapies for the autism-linked condition Rett syndrome.
Huda Zoghbi: Taking genetic inquiry to the next level
Over the course of a career spanning more than three decades, Huda Zoghbi has won almost every major biology and neuroscience research award that exists. More than 20 years since she discovered the gene behind Rett syndrome, she remains laser focused on unlocking the condition’s secrets and finding effective treatments.
Huda Zoghbi: Taking genetic inquiry to the next level
Over the course of a career spanning more than three decades, Huda Zoghbi has won almost every major biology and neuroscience research award that exists. More than 20 years since she discovered the gene behind Rett syndrome, she remains laser focused on unlocking the condition’s secrets and finding effective treatments.
Alternative gene-therapy approaches take aim at Rett syndrome
Methods that selectively increase levels of the Rett protein make for safer and more effective treatment strategies, some researchers say.
Alternative gene-therapy approaches take aim at Rett syndrome
Methods that selectively increase levels of the Rett protein make for safer and more effective treatment strategies, some researchers say.
Explore more from The Transmitter
Neuroscience conference policy draws confusion, apology
NeurIPS organizers apologized and altered course after issuing a policy that barred submissions from researchers at U.S.-government-sanctioned institutions.
Neuroscience conference policy draws confusion, apology
NeurIPS organizers apologized and altered course after issuing a policy that barred submissions from researchers at U.S.-government-sanctioned institutions.
Funding for animal research alternatives reaches ‘inflection point’
The United States and Europe are dedicating hundreds of millions of dollars in funding to advance novel alternative methods, but not all neuroscientists see this as a positive step.
Funding for animal research alternatives reaches ‘inflection point’
The United States and Europe are dedicating hundreds of millions of dollars in funding to advance novel alternative methods, but not all neuroscientists see this as a positive step.
‘Friction-maxxing’ in school: Students should read primary literature, not AI summaries
Trainees need to learn how to identify a neuroscience paper’s major takeaways and integrate them into their understanding. This skill doesn’t come from outsourcing the work to large language models.
‘Friction-maxxing’ in school: Students should read primary literature, not AI summaries
Trainees need to learn how to identify a neuroscience paper’s major takeaways and integrate them into their understanding. This skill doesn’t come from outsourcing the work to large language models.