Ion channels

Recent articles

How energy determines where proteins are produced in neurons

Tatjana Tchumatchenko explains how mathematical modeling elucidates whether ion-channel proteins are produced locally in the soma or in the dendrites.

By Gaute Einevoll
26 August 2026 | 104 min listen
Annette Dolphin.

Remembering Annette Dolphin, who helped explain gabapentin’s effects

The "intuitive" neuropharmacologist pushed against the status quo.

By Michael Eisenstein
13 March 2026 | 7 min read
Stack of papers.

What are the most-cited neuroscience papers from the past 30 years?

Highly cited papers reflect the surge in artificial-intelligence research in the field and other technical advances, plus prizewinning work on analgesics, the fusiform face area and ion channels.

By The Transmitter
15 November 2025 | 11 min read
Illustration of ketamine blocking open ion channels in active NMDA receptors, quieting the cells and disrupting downstream signaling involved in depression.

Ketamine targets lateral habenula, setting off cascade of antidepressant effects

The drug’s affinity for overactive cells in the “anti-reward” region may help explain its rapid and long-lasting results.

By Olivia Gieger
4 September 2024 | 6 min read
Photograph of Theanne Griffith sitting at a table with her hands interlocked over a stack of books, with one that she has published at the very top.

Crafting tales of science with Theanne Griffith

A lifelong passion for writing helped the neuroscientist land a book deal and publish 15 chapter books for early readers, covering topics ranging from what the cerebellum does to how a cake bakes.

By Angie Voyles Askham
26 August 2024 | 8 min read
Research image of two fluorescent-stained organoids.

CRISPR gives autism-linked genes a boost, rescues functioning

A modified form of the gene-editing tool increases the expression of CHD8 and SCN2A, showing potential for autism therapies.

By Giorgia Guglielmi
23 May 2024 | 5 min read
Research image of microglia in mice.

Microglial overreaction to atypical neurons may drive autism

In mice and organoids lacking a neuronal protein, microglia prune synapses to excess.

By Holly Barker
21 March 2024 | 5 min read
Black-and-white photograph of William Catterall in a lab.

The legacy of William Catterall, ‘father of ion channels’

Catterall, who characterized the structure, function and regulation of sodium and calcium channels crucial for neuronal excitability, died last month at the age of 77.

By Calli McMurray
12 March 2024 | 7 min read
A research image of neuronal dendrites in mice.

Top autism-linked genes join forces to shape synaptic plasticity

The protein products of ANK2 and SCN2A interact to regulate dendritic excitability.

By Holly Barker
29 January 2024 | 4 min read
Figure shows cultured human kidney cells and cultured rat cortical neurons responding to light exposure.

Unconventional optogenetics technique spurs long-lasting changes in neuronal activity

Conventional optogenetic manipulations to excite or inhibit neurons stop when the light switches off. A new approach makes the changes last.

By Peter Hess
9 January 2023 | 4 min read

Explore more from The Transmitter

leech illustration.

What leeches reveal about movement

Lidia Szczupak turned to the animals to explore how the nervous system coordinates movement.

By Claudia López Lloreda
27 August 2026 | 6 min read
Illustration of scientist facing a fractured landscape.

Redefining underrepresentation in global neuroscience

Shifting the focus of equity initiatives from identity categories to structural barriers can reveal overlooked challenges and increase support and participation worldwide.

Illustration of scientists climbing over a barrier to reach publications.

Scientific talent is global. Access to the world’s scientific stage is not.

Neuroscience in Chile, and across Latin America, does not lack talent or ideas, but the systems that make science visible—prestigious journals, conferences and networks—increasingly price its researchers out.

By Vicente Medel
27 August 2026 | 8 min read