Spectrum

Spectrum is the go-to destination for the latest news and analysis about autism research and a springboard for scientists and clinicians to forge collaborations that deepen our understanding of autism.

Action potentials

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Upcoming meeting
June
17-21
2024
Suzhou, China
Autism & Neurodevelopment Disorders – from Genetic Discoveries to Interventions
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What we are reading
“Most Popular Autism Therapy May Not Work — and May Seriously Harm Patients’ Mental Health”
By Beth Hawkins in The74
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But unless autism research becomes diverse and global at the same time, we will retain the ‘knowledge gap’ between the high-income/English-speaking nations and the rest of the world. — Petrus De Vries

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Research video of a zebrafish larva (zoomed in on the gut) being given glucose.
Spectrum

On the periphery: Thinking ‘outside the brain’ offers new ideas about autism

Neuronal alterations outside the brain may help to explain a host of the condition’s characteristic traits, including sensory changes, gut problems and motor differences.

By Sarah DeWeerdt
13 April 2023 | 20 min read
Coraline with her family at home in Pennsylvania.
Spectrum

The promise of telehealth in autism diagnoses

The COVID-19 pandemic forced a reckoning, in which autism clinicians had to redefine best practices and expand how children are evaluated. The remote assessments they developed may help solve a persistent problem: the long wait families endure to get a diagnosis in the United States.

By Lydia Denworth
15 February 2023 | 22 min read
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Spectrum books

Chronicle of a Field Retold: Autism Science in Profile

2022
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Autism by the Numbers: Explaining its Apparent Rise

2021
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Spectrum’s guide to autism 2020

2020
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Research image of glutaminergic synapses on parvalbumin interneurons.

Brain Gene Registry; neurite density; income disparities in autism diagnoses

Here is a roundup of autism-related news and research spotted around the web for the week of 29 April.

By Jill Adams
30 April 2024 | 2 min read
Research image of antisense oligonucleotides.

RNA drug corrects calcium signaling in chimeric model of Timothy syndrome

The drug, tested in rats that have human neurons, could enter clinical testing as early as next year, researchers say.

By Katie Moisse
24 April 2024 | 5 min read

Reporting bias widespread in early-childhood autism intervention trials

Only 7 percent of completed registered trials were later updated with results, one of several failings identified in a new analysis.

By Gina Jiménez
18 April 2024 | 5 min read
Computer-generated image of a protein binding to another protein.

TRIO gene; left-handedness; gender diversity

Here is a roundup of autism-related news and research spotted around the web for the week of 15 April.

By Jill Adams
16 April 2024 | 2 min read
A digital rendering of a strand of RNA

New RNA editor boasts increased versatility, safety

The “PRECISE” technique reprograms cells in a way that, unlike DNA editors, avoids potentially permanent off-target effects.

By Charles Q. Choi
11 April 2024 | 4 min read

Explore more from The Transmitter

Research illustration groups genes by their effects on brain cell types.

Giant analysis reveals how autism-linked genes affect brain cell types

Genes that predispose people to autism account for a large portion of the neuronal and glial cell changes seen in those with the condition.

By Charles Q. Choi
20 June 2024 | 5 min read

Widely used calcium imaging protocol can lead to spurious results, new paper cautions

The technique, which measures calcium currents as a proxy for neuronal firing, sometimes reports unusual and potentially misleading waves of activity in the hippocampus.

By Angie Voyles Askham
19 June 2024 | 0 min watch
Image of a series of red sticky notes protruding from a stack of white paper.

Faked results lead to retraction of high-profile cancer neuroscience study

An investigation found that the experiments required more animals than the scientists had purchased.

By Dalmeet Singh Chawla
18 June 2024 | 4 min read