CRISPR
Recent articles
Supported by a $40 million NIH grant, Yale brain shuttle technology raises questions
Yale University claims its STEP platform might be able to deliver gene-editing tools into the brain via multiple routes. Researchers are eager to see more.
Supported by a $40 million NIH grant, Yale brain shuttle technology raises questions
Yale University claims its STEP platform might be able to deliver gene-editing tools into the brain via multiple routes. Researchers are eager to see more.
Learning why spiny mice play well with others
Aubrey Kelly studies the gregarious mammal to explore how the brain controls complex social behaviors “akin to friendship.”
Learning why spiny mice play well with others
Aubrey Kelly studies the gregarious mammal to explore how the brain controls complex social behaviors “akin to friendship.”
Advances in genetic medicine took center stage at INSAR
The president of the Autism Science Foundation and parent of a child with profound autism reflects on how advances in the treatment of rare gene variants bring hope to many families.
Advances in genetic medicine took center stage at INSAR
The president of the Autism Science Foundation and parent of a child with profound autism reflects on how advances in the treatment of rare gene variants bring hope to many families.
Nearly 400 compounds affect behaviors tied to autism-linked genes in zebrafish
Estropipate, paclitaxel and levocarnitine altered behaviors tied to SCN2A and DYRK1A variants specifically, a new open-source platform revealed.
Nearly 400 compounds affect behaviors tied to autism-linked genes in zebrafish
Estropipate, paclitaxel and levocarnitine altered behaviors tied to SCN2A and DYRK1A variants specifically, a new open-source platform revealed.
Boosting SCN2A expression reduces seizures in mice
A modified form of CRISPR amps up expression of the gene—a strategy that could apply to other gene variations linked to autism.
Boosting SCN2A expression reduces seizures in mice
A modified form of CRISPR amps up expression of the gene—a strategy that could apply to other gene variations linked to autism.
Cell ‘antennae’ link autism, congenital heart disease
Variants in genes tied to both conditions derail the formation of cilia, the tiny hair-like structure found on almost every cell in the body, a new study finds.
Cell ‘antennae’ link autism, congenital heart disease
Variants in genes tied to both conditions derail the formation of cilia, the tiny hair-like structure found on almost every cell in the body, a new study finds.
Opioid receptors may guide formation of gut nervous system in zebrafish
Fish lacking functional copies of the receptors have fewer enteric neurons than usual, but the findings await further validation.
Opioid receptors may guide formation of gut nervous system in zebrafish
Fish lacking functional copies of the receptors have fewer enteric neurons than usual, but the findings await further validation.
CRISPR gives autism-linked genes a boost, rescues functioning
A modified form of the gene-editing tool increases the expression of CHD8 and SCN2A, showing potential for autism therapies.
CRISPR gives autism-linked genes a boost, rescues functioning
A modified form of the gene-editing tool increases the expression of CHD8 and SCN2A, showing potential for autism therapies.
Cocaine, morphine commandeer neurons normally activated by food, water in mice
Confirming a long-held hypothesis, repeated exposure to the drugs alters neurons in the nucleus accumbens, the brain’s reward center, and curbs an animal’s urge for sustenance.
Cocaine, morphine commandeer neurons normally activated by food, water in mice
Confirming a long-held hypothesis, repeated exposure to the drugs alters neurons in the nucleus accumbens, the brain’s reward center, and curbs an animal’s urge for sustenance.
New RNA editor boasts increased versatility, safety
The “PRECISE” technique reprograms cells in a way that, unlike DNA editors, avoids potentially permanent off-target effects.
New RNA editor boasts increased versatility, safety
The “PRECISE” technique reprograms cells in a way that, unlike DNA editors, avoids potentially permanent off-target effects.
Explore more from The Transmitter
The fast-expanding repertoire of mitochondria in the brain
More than cellular powerhouses, these organelles also seem to help synapses communicate, support memory formation and even shape behavior.
The fast-expanding repertoire of mitochondria in the brain
More than cellular powerhouses, these organelles also seem to help synapses communicate, support memory formation and even shape behavior.
When autistic kids grow up, Chapter 5: The war dial
“You have to reshape the whole system.” Tempest McDonald earns a measure of peace.
When autistic kids grow up, Chapter 5: The war dial
“You have to reshape the whole system.” Tempest McDonald earns a measure of peace.
Scientists decry conference’s use of hidden prompts to snare AI peer reviews
The invisible messages, which instruct large language models to use telltale phrases in a peer-review report, are effective in catching artificial-intelligence misuse but also erode trust, some say.
Scientists decry conference’s use of hidden prompts to snare AI peer reviews
The invisible messages, which instruct large language models to use telltale phrases in a peer-review report, are effective in catching artificial-intelligence misuse but also erode trust, some say.