Developmental neuroscience
Recent articles
Early experience reshapes zebrafish retinal cells, alters behavior
The cells undergo a classic form of plasticity previously thought to occur only in downstream visual circuits.
Early experience reshapes zebrafish retinal cells, alters behavior
The cells undergo a classic form of plasticity previously thought to occur only in downstream visual circuits.
How thirteen-lined ground squirrels illuminate retinal development
In most mammalian retinas, rods outnumber cones. But that ratio is flipped in ground squirrels, a quirk that helps Seth Blackshaw explore how retinal cells develop their identities.
How thirteen-lined ground squirrels illuminate retinal development
In most mammalian retinas, rods outnumber cones. But that ratio is flipped in ground squirrels, a quirk that helps Seth Blackshaw explore how retinal cells develop their identities.
Neurons engage in risky, DNA-breaking business during migration
The cells later repair the damage, which occurs mostly in transcriptionally silent parts of the genome.
Neurons engage in risky, DNA-breaking business during migration
The cells later repair the damage, which occurs mostly in transcriptionally silent parts of the genome.
This paper changed my life: Learning the molecular rules of cell identity
A 1987 Cell paper showed that a single transcription factor could turn fibroblasts into muscle cells. The work inspired Ardem Patapoutian to think about the molecular codes that define neuronal subtypes.
This paper changed my life: Learning the molecular rules of cell identity
A 1987 Cell paper showed that a single transcription factor could turn fibroblasts into muscle cells. The work inspired Ardem Patapoutian to think about the molecular codes that define neuronal subtypes.
Nearly 400 compounds affect behaviors tied to autism-linked genes in zebrafish
Estropipate, paclitaxel and levocarnitine altered behaviors tied to SCN2A and DYRK1A variants specifically, a new open-source platform revealed.
Nearly 400 compounds affect behaviors tied to autism-linked genes in zebrafish
Estropipate, paclitaxel and levocarnitine altered behaviors tied to SCN2A and DYRK1A variants specifically, a new open-source platform revealed.
Infant visual system categorizes common objects by 2 months of age
Brain activity patterns in the ventral visual cortex appear to distinguish images across 12 categories, including birds and trees, longitudinal functional MRI scans suggest.
Infant visual system categorizes common objects by 2 months of age
Brain activity patterns in the ventral visual cortex appear to distinguish images across 12 categories, including birds and trees, longitudinal functional MRI scans suggest.
Microglia implicated in infantile amnesia
The glial cells could explain the link between maternal immune activation and autism-like behaviors in mice.
Microglia implicated in infantile amnesia
The glial cells could explain the link between maternal immune activation and autism-like behaviors in mice.
Oligodendrocytes need mechanical cues to myelinate axons correctly
Without the mechanosensor TMEM63A, the cells cannot deposit the appropriate amount of insulation, according to a new study.
Oligodendrocytes need mechanical cues to myelinate axons correctly
Without the mechanosensor TMEM63A, the cells cannot deposit the appropriate amount of insulation, according to a new study.
Cell atlas cracks open ‘black box’ of mammalian spinal cord development
The atlas details the genetics, birth dates and gene-expression signatures of roughly 150 neuron subtypes in the dorsal horn of the mouse spinal cord.
Cell atlas cracks open ‘black box’ of mammalian spinal cord development
The atlas details the genetics, birth dates and gene-expression signatures of roughly 150 neuron subtypes in the dorsal horn of the mouse spinal cord.
Prenatal viral injections prime primate brain for study
The approach makes it possible to deploy tools such as CRISPR and optogenetics across the monkey brain before birth.
Prenatal viral injections prime primate brain for study
The approach makes it possible to deploy tools such as CRISPR and optogenetics across the monkey brain before birth.
Explore more from The Transmitter
This paper changed my life: A technical breakthrough for memory studies
In a 2007 Science paper, Mark Mayford and his colleagues found that some neurons activated during learning are also recruited during memory retrieval. Noelia Weisstaub shares how this study and others drove an era of great progress in tool development.
This paper changed my life: A technical breakthrough for memory studies
In a 2007 Science paper, Mark Mayford and his colleagues found that some neurons activated during learning are also recruited during memory retrieval. Noelia Weisstaub shares how this study and others drove an era of great progress in tool development.
Loss of interneuron plasticity may be shared hallmark of neurodevelopmental conditions
Restoring an experience-dependent interneuron plasticity gene in adulthood improves memory and cuts seizures in CNTNAP2 knockout mice, a new study shows.
Loss of interneuron plasticity may be shared hallmark of neurodevelopmental conditions
Restoring an experience-dependent interneuron plasticity gene in adulthood improves memory and cuts seizures in CNTNAP2 knockout mice, a new study shows.
Neuropsychiatric MRI brain signatures fail reproducibility test
Small neuroimaging studies are unlikely to capture consistent anatomical changes related to conditions such as autism, schizophrenia and mood disorders, according to a new “wake-up call” study.
Neuropsychiatric MRI brain signatures fail reproducibility test
Small neuroimaging studies are unlikely to capture consistent anatomical changes related to conditions such as autism, schizophrenia and mood disorders, according to a new “wake-up call” study.