Cortex

Recent articles

Research image of whole-brain 3D visualizations of pixels colored by their corresponding lipizone.

Lipids enter brain mapping limelight

Two new studies, including the first whole-brain lipid atlas in mice, uncover unforeseen complexity and influence during pregnancy and aging.

By Lauren Schenkman
27 October 2026 | 6 min read
Illustration of a person standing in a crumbling room with papers and strings on the wall, a fallen chair, and a lamp.

What to do when traditional mechanistic approaches no longer work

Many complex behaviors have stubbornly resisted mechanistic explanations. Deciphering them will require new approaches—and perhaps a new concept of “understanding.”

By Bence Ölveczky
19 October 2026 | 8 min read
Headshots of Karl Deisseroth, Peter Hegemann and Georg Nagel.

How Nobel Prize-winning optogenetics has revolutionized neuroscience

The technique has enabled neuroscientists to target brain circuits and cells with unprecedented specificity, transforming the study of memory, interoception, brain disorders and reward, among other domains.

Research diagram of task-aligned activity rasters.

Cerebellar neurons reorient brain activity to differentiate similar behaviors

The findings provide a new perspective on how granule cells help to generalize learning across tasks.

By Holly Barker
29 September 2026 | 4 min read
Mouse cortical organoid.

Hasty stem cells highlight potential limitation with cortical organoids

The models recapitulate many key developmental processes, but some radial glial cells in mouse organoids make neurons earlier than they should.

By Giorgia Guglielmi
22 September 2026 | 4 min read
Nerve fibers from the human graft in mouse brain.

Human brain organoids flourish in emptied mouse cortex

The chimeric mice could help untangle the biology of human brain development or conditions such as autism.

By Brianna Abbott
16 September 2026 | 6 min read
Neuronal genes SATB2 and MEF2C.

Nuclear location helps control gene activity during brain development

A study of developing human brain tissue suggests that genes switch on more strongly when they move from the nucleus’s edge toward structures that contain proteins involved in making and processing RNA.

By Giorgia Guglielmi
20 August 2026 | 5 min read

Alison Barth discovers how different neuron types contribute to cortical function

Barth uses learning tasks in mice as a tool to drive synaptic plasticity in the sensory cortex, hoping to unlock more general principles of how the cortex works.

By Paul Middlebrooks
5 August 2026 | 1 min read
Research image of the association cortex.

Cortical territories compete in developmental space race

Sensory and association regions are established through a reciprocal process, according to a new model of cortical development.

By Holly Barker
30 July 2026 | 5 min read
Brain scans showing sex-based activation differences.

Brain’s sex differences are subtle and contradictory, large MRI study finds

Sex-based behavioral differences do not match with variations in brain activation or structure in a study of almost 1,000 people.

By Lauren Schenkman
8 July 2026 | 5 min read

Explore more from The Transmitter

Protein asparagine synthetase in hippocampus neurons.

Behavioral phenomics in zebrafish; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 26 October.

By Jill Adams
27 October 2026 | 2 min read
Illustration of botanical tree and computer tree growing apart.

Neuroscience gave AI its start. What happens now?

David Sussillo maps the two fields' divergent paths, and where they might still meet.

By Emily Singer
27 October 2026 | 10 min read
Illustration of a bridge shaped like minds.

Commentary: Citation graphs may underestimate neuroscience’s influence on AI

An alternative, albeit less quantitative, way to trace this history is through the people who carried ideas between the fields.

By Anthony Zador
26 October 2026 | 5 min read