Spectrum
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Spectrum is the go-to destination for the latest news and analysis about autism research and a springboard for scientists and clinicians to forge collaborations that deepen our understanding of autism.
Autism-linked variants converge on two molecular patterns in mouse brains
Polarized cortical organoids mimic the brain’s regional organization
Organoids missing the TSC2 gene form rogue astrocytes; and more
Action potentials
”Replacing a substantial portion of an animal brain with human neural tissue represents an impressive technical advance. — IN-HYUN PARK, ASSOCIATE PROFESSOR OF GENETICS AND NEUROSCIENCE, YALE SCHOOL OF MEDICINE
Finding the Rett syndrome gene and ways to fix it
How basic neuroscientists can connect with autistic people and their communities
Advances in genetic medicine took center stage at INSAR
Exon-skipping approach boosts levels of key Rett syndrome protein
Molecular changes after MECP2 loss may drive Rett syndrome traits
Exclusive: Who is Richard Frye, the neurologist who researches and advocates for leucovorin as an autism treatment?
Frye has led two placebo-controlled trials of the folate supplement in autistic people; the first was suspended by regulators, and the other has yet to be published.
Neuroscientist Gerry Fischbach, in his own words
In 2023, I had the privilege of sitting down with Gerry over the course of several days and listening as he told the story of his life and career—including stints as dean or director of such leading institutions as Columbia University and NINDS—so that we could record it for posterity.
CDC autism prevalence numbers warrant attention—but not in the way RFK Jr. proposes
Autism prevalence increasing in children, adults, according to electronic medical records
High prevalence of developmental delay strains Australia’s support systems
Reimagining Mexico’s brain bank
Reimaginando el banco de cerebros de México
Decisional capacity and informed consent, explained
The link between maternal infection and autism, explained
Pathological demand avoidance in autism, explained
The connection between oxytocin and autism, explained
Spectrum books
Two populations of neurons, two effects on sociability; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 21 September.
Two populations of neurons, two effects on sociability; and more
Here is a roundup of autism-related news and research spotted around the web for the week of 21 September.
Sylvia Fogel, reshaping U.S. autism research strategy
In a wide-ranging and provocative interview, the chair of the federal Interagency Autism Coordinating Committee shares her views on vaccines, regression, neuroimmune conditions and more.
Sylvia Fogel, reshaping U.S. autism research strategy
In a wide-ranging and provocative interview, the chair of the federal Interagency Autism Coordinating Committee shares her views on vaccines, regression, neuroimmune conditions and more.
Human brain organoids flourish in emptied mouse cortex
The chimeric mice could help untangle the biology of human brain development or conditions such as autism.
Human brain organoids flourish in emptied mouse cortex
The chimeric mice could help untangle the biology of human brain development or conditions such as autism.
Additional data suggest changes in diagnostics underlie increases in autism diagnoses, and more
Here is a roundup of autism-related news and research spotted around the web for the week of 14 September.
Additional data suggest changes in diagnostics underlie increases in autism diagnoses, and more
Here is a roundup of autism-related news and research spotted around the web for the week of 14 September.
Sensory over-responsivity tied to autism, anxiety but not other conditions
Negative reactions to sensations track with certain neurodevelopmental traits in more than 15,000 children—pointing to shared neurobiological roots.
Sensory over-responsivity tied to autism, anxiety but not other conditions
Negative reactions to sensations track with certain neurodevelopmental traits in more than 15,000 children—pointing to shared neurobiological roots.
Explore more from The Transmitter
How Nobel Prize-winning optogenetics has revolutionized neuroscience
The technique has enabled neuroscientists to target brain circuits and cells with unprecedented specificity, transforming the study of memory, interoception, brain disorders and reward, among other domains.
How Nobel Prize-winning optogenetics has revolutionized neuroscience
The technique has enabled neuroscientists to target brain circuits and cells with unprecedented specificity, transforming the study of memory, interoception, brain disorders and reward, among other domains.
Is confidence a second thought—or part of the first one?
In some settings, neural circuits may calculate confidence in a decision simultaneously with the choice itself. That changes the types of questions researchers should ask.
Is confidence a second thought—or part of the first one?
In some settings, neural circuits may calculate confidence in a decision simultaneously with the choice itself. That changes the types of questions researchers should ask.
What AI can learn from hunger
To enhance AI safety, take a lesson from biological brains; a small set of wants maintains durable control over a much larger cognitive system.
What AI can learn from hunger
To enhance AI safety, take a lesson from biological brains; a small set of wants maintains durable control over a much larger cognitive system.