Spectrum

Recent articles

Spectrum is the go-to destination for the latest news and analysis about autism research and a springboard for scientists and clinicians to forge collaborations that deepen our understanding of autism.

Action potentials

Image
Upcoming event
OCTOBER
26
2026
ONLINE (ZOOM)
Autism in Latin America: Practices, Supports, and Local Realities
26 OCTOBER 2026
Read more
Quote
”

Replacing a substantial portion of an animal brain with human neural tissue represents an impressive technical advance. — IN-HYUN PARK, ASSOCIATE PROFESSOR OF GENETICS AND NEUROSCIENCE, YALE SCHOOL OF MEDICINE

Read more
WHAT WE ARE READING
“Grandparents’ Age Sheds Light on Autism Spectrum Disorder Risk Mechanisms in Their Grandchildren”
By DONNA M. WERLING in Biological Psychiatry
READ MORE

Sign up for the weekly Spectrum newsletter.

Stay current with the latest advancements in autism research.

Richard Frye.
Spectrum

Exclusive: Who is Richard Frye, the neurologist who researches and advocates for leucovorin as an autism treatment?

Frye has led two placebo-controlled trials of the folate supplement in autistic people; the first was suspended by regulators, and the other has yet to be published.

By Brendan Borrell
1 October 2025 | 11 min read
Gerry Fischbach.
Neuroscience

Neuroscientist Gerry Fischbach, in his own words

In 2023, I had the privilege of sitting down with Gerry over the course of several days and listening as he told the story of his life and career—including stints as dean or director of such leading institutions as Columbia University and NINDS—so that we could record it for posterity.

By Ivan Oransky
30 May 2025 | 2 min read
See all Profiles See all Profiles - opens a new tab
Cerebellar Purkinje cells.

Aging biomarkers in autism; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 5 October.

By Jill Adams
6 October 2026 | 2 min read
Illustration of DNA with genetic code.

Autism-linked variants converge on two molecular patterns in mouse brains

Gene activity across 17 autism mouse models occurs in either of two opposing transcriptomic states, supporting the idea that diverse genetic changes may converge on a few recurring biological patterns.

By Giorgia Guglielmi
1 October 2026 | 4 min read
Research image of perineuronal nets.

Organoids missing the TSC2 gene form rogue astrocytes; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 28 September.

By Jill Adams
29 September 2026 | 2 min read
Cortical organoids from the anterior (green) or posterior (red) cortex.

Polarized cortical organoids mimic the brain’s regional organization

The organoids show region-specific gene-expression changes that match those observed during fetal development.

By Holly Barker
24 September 2026 | 4 min read
Illustration of an open journal featuring lines of text and small illustrations of eyes and mouths.

Two populations of neurons, two effects on sociability; and more

Here is a roundup of autism-related news and research spotted around the web for the week of 21 September.

By Jill Adams
22 September 2026 | 2 min read

Explore more from The Transmitter

Fiona Sanderson photo illustration.

Creating community through grant support

Fiona Sanderson, a senior program manager at the Brain Canada Foundation, shares how she got into grant administration and how she helps connect researchers with funding and one another.

By Katie Moisse
14 October 2026 | 7 min read
Illustration of the brain processing different shapes.

This paper changed my life: A first glimpse into the ‘middle’ of brain processing

Work by Jeffrey Moran and Robert Desimone showed that monkeys could focus their attention on different stimuli in their visual field without shifting their gaze. Their work marked a key milestone in the emergence of cognitive neuroscience.

By Earl K. Miller
14 October 2026 | 3 min read
Edgar Adrian works in the laboratory, around 1920.

The neural code at 100

In two 1926 articles, Edgar Douglas Adrian revealed that neurons communicate through trains of spikes.

By Matteo Carandini
12 October 2026 | 8 min read